Zebrafish-based platform for emerging bio-contaminants and virus inactivation research

P Patel, A Nandi, SK Verma, N Kaushik, M Suar… - Science of The Total …, 2023 - Elsevier
Emerging bio-contaminants such as viruses have affected health and environment settings
of every country. Viruses are the minuscule entities resulting in severe contagious diseases …

Zebrafish as a model organism for virus disease research: Current status and future directions

S Fajar, SP Dwi, IS Nur, AP Wahyu, AR Winda… - Heliyon, 2024 - cell.com
Zebrafish (Danio rerio) have emerged as valuable models for investigating viral infections,
providing insights into viral pathogenesis, host responses, and potential therapeutic …

Intranasal delivery of SARS-CoV-2 spike protein is sufficient to cause olfactory damage, inflammation and olfactory dysfunction in zebrafish

A Kraus, M Huertas, L Ellis, P Boudinot… - Brain, behavior, and …, 2022 - Elsevier
Anosmia, loss of smell, is a prevalent symptom of SARS-CoV-2 infection. Anosmia may be
explained by several mechanisms driven by infection of non-neuronal cells and damage in …

Polystyrene nanoplastics induced size-dependent developmental and neurobehavioral toxicities in embryonic and juvenile zebrafish

J Chen, Q Liang, Y Zheng, Y Lei, X Gan, H Mei, C Bai… - Aquatic Toxicology, 2024 - Elsevier
Because of widespread environmental contamination, there is growing concern that
nanoplastics may pose a risk to humans and the environment. Due to their small particle …

Neuromasts and olfactory organs of zebrafish larvae represent possible sites of SARS-Cov-2 pseudovirus host cell entry

SSA Choi, HH Chan, CM Chan, X Wang… - Journal of …, 2022 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the acute respiratory disease coronavirus disease 2019 (COVID-19), which has resulted in …

A novel insight on SARS-CoV-2 S-derived fragments in the control of the host immunity

TSB Bastos, AGP de Paula, RB dos Santos Luz… - Scientific reports, 2023 - nature.com
Despite all efforts to combat the pandemic of COVID-19, we are still living with high numbers
of infected persons, an overburdened health care system, and the lack of an effective and …

Pannexin channel 1, P2× 7 receptors, and Dimethyl Sulfoxide mediate pain responses in zebrafish

D Gusso, FF Cruz, PM Fritsch, MO Gobbo… - Behavioural Brain …, 2022 - Elsevier
The zebrafish has been considered an ideal model for studies of complex behaviors since
its behavioral repertoire is well described. Therefore, this study evaluated the perceived pain …

Animal models for studying COVID-19, prevention, and therapy: Pathology and disease phenotypes

S Choudhary, I Kanevsky… - Veterinary Pathology, 2022 - journals.sagepub.com
Translational models have played an important role in the rapid development of safe and
effective vaccines and therapeutic agents for the ongoing coronavirus disease 2019 (COVID …

Role of the nucleoside-metabolizing enzymes on pain responses in zebrafish larvae

D Gusso, MT Wiprich, S Altenhofen… - Neurotoxicology and …, 2022 - Elsevier
Purinergic signaling is a pathway related to pain underlying mechanisms. Adenosine is a
neuromodulator responsible for the regulation of multiple physiological and pathological …

[HTML][HTML] Application of the zebrafish model in human viral research

J Liu, X Yuan, C Fan, G Ma - Virus Research, 2024 - Elsevier
Viruses are a leading cause of infectious diseases. Well-developed animal models are
valuable for understanding the immune responses to viral infections and the pathogenesis …