Antibiotic resistance in Chlamydiae

KM Sandoz, DD Rockey - Future microbiology, 2010 - Taylor & Francis
There are few documented reports of antibiotic resistance in Chlamydia and no examples of
natural and stable antibiotic resistance in strains collected from humans. While there are …

Human and pathogen factors associated with Chlamydia trachomatis-related infertility in women

S Menon, P Timms, JA Allan, K Alexander… - Clinical microbiology …, 2015 - Am Soc Microbiol
Chlamydia trachomatis is the most common bacterial sexually transmitted pathogen
worldwide. Infection can result in serious reproductive pathologies, including pelvic …

Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing

SR Harris, IN Clarke, HMB Seth-Smith, AW Solomon… - Nature …, 2012 - nature.com
Chlamydia trachomatis is responsible for both trachoma and sexually transmitted infections,
causing substantial morbidity and economic cost globally. Despite this, our knowledge of its …

Reductionistic and holistic science

FC Fang, A Casadevall - Infection and immunity, 2011 - Am Soc Microbiol
ABSTRACT A reductionistic approach to science, epitomized by molecular biology, is often
contrasted with the holistic approach of systems biology. However, molecular biology and …

Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes

L Song, JH Carlson, WM Whitmire, L Kari… - Infection and …, 2013 - Am Soc Microbiol
Chlamydia trachomatis causes chronic inflammatory diseases of the eye and genital tract
and has global medical importance. The chlamydial plasmid plays an important role in the …

Chlamydial infection from outside to inside

A Gitsels, N Sanders, D Vanrompay - Frontiers in Microbiology, 2019 - frontiersin.org
Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic
developmental cycle. Specific interactions with the host cell are crucial for the bacteria's …

Evolution, phylogeny, and molecular epidemiology of Chlamydia

A Nunes, JP Gomes - Infection, Genetics and Evolution, 2014 - Elsevier
The Chlamydiaceae are a family of obligate intracellular bacteria characterized by a unique
biphasic developmental cycle. It encompasses the single genus Chlamydia, which involves …

Lymphogranuloma venereum among men who have sex with men. An epidemiological and clinical review

NHN De Vrieze, HJC De Vries - Expert review of anti-infective …, 2014 - Taylor & Francis
Lymphogranuloma venereum (LGV) is a sexually transmitted infection, previously only seen
in tropical regions. This changed in 2003 when the first endemically acquired LGV cases …

Chlamydia genomics: providing novel insights into chlamydial biology

NL Bachmann, A Polkinghorne, P Timms - Trends in microbiology, 2014 - cell.com
Chlamydiaceae are obligate intracellular pathogens that have successfully evolved to
colonize a diverse range of hosts. There are currently 11 described species of Chlamydia …

Whole-genome sequences of Chlamydia trachomatis directly from clinical samples without culture

HMB Seth-Smith, SR Harris, RJ Skilton… - Genome …, 2013 - genome.cshlp.org
The use of whole-genome sequencing as a tool for the study of infectious bacteria is of
growing clinical interest. Chlamydia trachomatis is responsible for sexually transmitted …