The hippocampus (HPC) controls fundamental learning and memory processes, including memory for visuospatial navigation (spatial memory) and flexible memory for facts and …
N dos Santos Tramontin, S da Silva, R Arruda… - Molecular …, 2020 - Springer
Alzheimer's disease (AD) is characterized by amyloid (A) β peptide accumulation and intracellular neurofibrillary tangles. New hypotheses have suggested that AD involves …
This study aimed to prepare and characterize chitosan-Transfersulin (CTI) as an effective intranasal drug delivery system (IDDS) for the treatment of memory disorders by mediating …
AM Elfiky, AA Mahmoud, HA Elreedy, KS Ibrahim… - Life sciences, 2021 - Elsevier
Aims Alzheimer's disease (AD) is the most common progressive neurodegenerative disorder characterized by declined cognitive functions in the elderly. Quercetin (Q) is a potent …
K Pierzynowska, M Podlacha, L Gaffke, I Majkutewicz… - …, 2019 - Elsevier
Alzheimer's disease is one of severe neurological diseases for which no effective treatment is currently available. The use of genistein (5, 7-dihydroxy-3-(4-hydroxyphenyl)-4H-1 …
Thymoquinone (TQ) is a potent phytoconstituent from Nigella sativa and well recognized for its neuroactivity via antioxidant mechanisms, but its higher lipophilicity and plasma protein …
JH Kim, R Afridi, J Han, HG Jung, SC Kim, EM Hwang… - Brain, 2021 - academic.oup.com
The complement system is part of the innate immune system that comprises several small proteins activated by sequential cleavages. The majority of these complement components …
Sporadic Alzheimer's disease (SAD) is the most common form of dementia; therefore, there is an urgent need for a model that recapitulates the main pathologic hallmarks of this …
Intracerebroventricularly (icv) injected streptozotocin (STZ) model of Alzheimer's disease (AD) is used to explore the effect of intermittent theta burst stimulation (iTBS) on astrocyte …