Osteoarticular mycoses are chronic debilitating infections that require extended courses of
antifungal therapy and may warrant expert surgical intervention. As there has been no …

Poly (methyl methacrylate)(PMMA) is one of the most widely explored biomedical materials
because of its biocompatibility, and recent publications have shown an increasing interest in …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Management of fungal osteomyelitis and fungal septic arthritis is challenging, especially in
the setting of immunodeficiency and conditions that require immunosuppression. Because …

Disadvantages of conventional drug delivery systems (DDS), such as systemic circulation,
interaction with physiochemical factors, reduced bioavailability, and insufficient drug …

During combat operations, extremities continue to be the most common sites of injury with
associated high rates of infectious complications. Overall,∼ 15% of patients with extremity …

Invasive Candida infections are important causes of morbidity and mortality in
immunocompromised and hospitalised patients. This article provides the joint …

The use of high doses of antibacterial and anti-inflammatory drugs for patients with bone
diseases, associated to implants or bone filling, can develop adverse effects; and …

Fungal periprosthetic joint infection (PJI) is a devastating complication because it can be
difficult to diagnose, manage, and eradicate. Fungal PJI treatment requires a systematic …

Fungal osteoarticular infections (OAI) are unusual but often destructive infections requiring
surgery and prolonged antifungal therapy. These infections involve bone, joints, muscle, and …