Research progress of polycyclic polyprenylated acylphloroglucinols

XW Yang, RB Grossman, G Xu - Chemical reviews, 2018 - ACS Publications
Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of hybrid natural products
sharing the mevalonate/methylerythritol phosphate and polyketide biosynthetic pathways …

Phloroglucinol compounds of natural origin: Synthetic aspects

IP Singh, J Sidana, SB Bharate, WJ Foley - Natural product reports, 2010 - pubs.rsc.org
Phloroglucinol compounds of natural origin: Synthetic aspects - Natural Product Reports (RSC
Publishing) DOI:10.1039/B914364P Royal Society of Chemistry View PDF VersionPrevious …

Total Synthesis of Hypersampsone M

AE Samkian, SC Virgil, BM Stoltz - Journal of the American …, 2024 - ACS Publications
We report the first total synthesis of hypersampsone M, an archetypal member of the
homoadamantane polycyclic polyprenylated acylphloroglucinols (PPAPs). Commencing …

The chemistry of the polycyclic polyprenylated acylphloroglucinols

JA Richard, RH Pouwer… - Angewandte Chemie …, 2012 - Wiley Online Library
With their fascinating biological profiles and stunningly complex molecular architectures, the
polycyclic polyprenylated acylphloroglucinols (PPAPs) have long provided a fertile playing …

Catalytic Asymmetric Total Synthesis of ent‐Hyperforin

Y Shimizu, SL Shi, H Usuda, M Kanai, M Shibasaki - Angewandte Chemie, 2010 - infona.pl
Ein Erfolg mit vielen Vätern: Die erste katalytische asymmetrische Totalsynthese von ent‐
Hyperforin (siehe Bild) nutzt eine Diels‐Alder‐Reaktion in Gegenwart eines chiralen …

Enantioselective total synthesis of hyperforin

BA Sparling, DC Moebius, MD Shair - Journal of the American …, 2013 - ACS Publications
A modular, 18-step total synthesis of hyperforin is described. The natural product was
quickly accessed using latent symmetry elements, whereby a group-selective, Lewis acid …

[图书][B] Biomimetic organic synthesis

E Poupon, B Nay - 2011 - books.google.com
In this exciting 2 volume set, the approach and methodology of bio-inspired synthesis of
complex natural products is laid out, backed by abundant practical examples from the …

Total synthesis of hyperforin

CP Ting, TJ Maimone - Journal of the American Chemical Society, 2015 - ACS Publications
A 10-step total synthesis of the polycyclic polyprenylated acylphloroglucinol (PPAP) natural
product hyperforin from 2-methylcyclopent-2-en-1-one is reported. This route was enabled …

Rapid Access to Polyprenylated Phloroglucinols via Alkylative Dearomatization− Annulation: Total Synthesis of (±)-Clusianone

J Qi, JA Porco - Journal of the American Chemical Society, 2007 - ACS Publications
A concise approach to the bicyclo [3.3. 1] nonane framework of the polyprenylated
phloroglucinol natural products utilizing a tandem alkylative dearomatization− annulation …

The total synthesis of hyperpapuanone, hyperibone L, epi-clusianone and oblongifolin A

N Biber, K Möws, B Plietker - Nature chemistry, 2011 - nature.com
Polyprenylated polycyclic acylphloroglucines (PPAPs) are a family of natural products that
possess a wide range of different important biological activities because of the relative …