Vitamin D-mediated regulation of intestinal calcium absorption

JC Fleet - Nutrients, 2022 - mdpi.com
Vitamin D is a critical regulator of calcium and bone homeostasis. While vitamin D has
multiple effects on bone and calcium metabolism, the regulation of intestinal calcium (Ca) …

Vitamin A, D, E, and K as Matrix Metalloproteinase-2/9 regulators that affect expression and enzymatic activity

HVT Vo, YT Nguyen, N Kim, HJ Lee - International journal of molecular …, 2023 - mdpi.com
Fat-soluble vitamins (vitamin A, D, E, and K) assume a pivotal role in maintaining human
homeostasis by virtue of their enzymatic functions. The daily inclusion of these vitamins is …

Methotrexate Chemotherapy Causes Growth Impairments, Vitamin D Deficiency, Bone Loss, and Altered Intestinal Metabolism—Effects of Calcitriol Supplementation

YW Su, AMC Lee, X Xu, B Hua, H Tapp, XS Wen… - Cancers, 2023 - mdpi.com
Simple Summary Vitamin D deficiency or insufficiency is prevalent in childhood cancer
patients and survivors; however, the underlying etiology and effectiveness of vitamin D …

[HTML][HTML] 1,25-Dihydroxyvitamin D Enhances the Regenerative Function of Lgr5+ Intestinal Stem Cells In Vitro and In Vivo

NA Shaikh, C Liu, Y Yin, DJ Baylink, X Tang - Cells, 2024 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder in the intestines without
a cure. Current therapies suppress inflammation to prevent further intestinal damage …

Dynamic RNA polymerase II occupancy drives differentiation of the intestine under the direction of HNF4

K Vemuri, S Kumar, L Chen, MP Verzi - Cell Reports, 2024 - cell.com
Terminal differentiation requires massive restructuring of the transcriptome. During intestinal
differentiation, the expression patterns of nearly 4,000 genes are altered as cells transition …

The Role and Mechanism of RNA-binding Proteins in Bone Metabolism and Osteoporosis

J Wu, L Niu, K Yang, J Xu, D Zhang, J Ling, P Xia… - Ageing Research …, 2024 - Elsevier
Osteoporosis is a prevalent chronic metabolic bone disease that poses a significant risk of
fractures or mortality in elderly individuals. Its pathophysiological basis is often attributed to …

Highlights from the 24th workshop on vitamin D in Austin, September 2022

MB Meyer, C Bernal-Mizrachi, DD Bikle… - The Journal of steroid …, 2023 - Elsevier
Highlights from the 24th workshop on vitamin D in Austin, September 2022 - ScienceDirect
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Regulation of intestinal calcium and phosphate absorption by vitamin D

JC Fleet, S Christakos, H Jiang - Feldman and Pike's Vitamin D, 2024 - Elsevier
Efficient intestinal calcium (Ca) and phosphate (Pi) absorption is necessary for optimal bone
mineralization during growth, the protection of bone in adults, and the prevention of …

[HTML][HTML] Dynamic RNA Polymerase II Recruitment Drives Differentiation of the Intestine under the direction of HNF4

K Vemuri, S Kumar, L Chen, MP Verzi - bioRxiv, 2023 - ncbi.nlm.nih.gov
Terminal differentiation requires a massive restructuring of the transcriptome. During
intestinal differentiation, the expression patterns of nearly 4000 genes are altered as cells …

Evaluating Performance of IsoformSwitchAnalyzeR and mRNA Isoform Switching in Small Intestine Epithelial Differentiation

R Aita, L Chen, MP Verzi - Gastro hep advances, 2023 - ghadvances.org
1078 Aita et al Gastro Hep Advances Vol. 2, Iss. 8 isoform switch (q value< 0.001) in 3
conditions: Veh vs BMP2 treated organoids, TA cells vs AEs, and ISCs vs AEs. We see …