Amino acid transporters (AATs) are membrane-bound transport proteins that mediate
transfer of amino acids into and out of cells or cellular organelles. AATs have diverse …

Epilepsy is a complex neurological syndrome characterized by seizures resulting from
neuronal hyperexcitability and sudden and synchronized bursts of electrical discharges …

Retinal ischemia is a common cause of visual impairment and blindness. At the cellular
level, ischemic retinal injury consists of a self-reinforcing destructive cascade involving …

l-Glutamate is the predominant excitatory neurotransmitter in the mammalian central
nervous system and plays important roles in a wide variety of brain functions, but it is also a …

Reactive astrogliosis has long been recognized as a ubiquitous feature of CNS pathologies.
Although its roles in CNS pathology are only beginning to be defined, genetic tools are …

This review considers how recent advances in the physiology of ion channels and other
potential molecular targets, in conjunction with new information on the genetics of idiopathic …

Glutamate transporters play important roles in the termination of excitatory
neurotransmission and in providing cells throughout the body with glutamate for metabolic …

l‐Glutamate (Glu) is the major excitatory neurotransmitter in the mammalian CNS and five
types of high‐affinity Glu transporters (EAAT1–5) have been identified. The transporters …

Glutamate is the predominant excitatory neurotransmitter in the central nervous system.
Excitatory amino acid transporter 2 (EAAT2) is primarily responsible for clearance of …

Abstract l‐glutamate is the predominant excitatory neurotransmitter in the CNS and has a
central role in a variety of brain functions. The termination of glutamate neurotransmission by …