Medulloblastoma

PA Northcott, GW Robinson, CP Kratz… - Nature reviews Disease …, 2019 - nature.com
Medulloblastoma (MB) comprises a biologically heterogeneous group of embryonal tumours
of the cerebellum. Four subgroups of MB have been described (WNT, sonic hedgehog …

Platinum‐induced peripheral neurotoxicity: from pathogenesis to treatment

NP Staff, G Cavaletti, B Islam… - Journal of the …, 2019 - Wiley Online Library
Platinum‐induced peripheral neurotoxicity (PIPN) is a common side effect of platinum‐
based chemotherapy that may cause dose reduction and discontinuation, with oxaliplatin …

[HTML][HTML] Medulloblastoma in the modern era: review of contemporary trials, molecular advances, and updates in management

MA Lazow, JD Palmer, M Fouladi, R Salloum - Neurotherapeutics, 2022 - Elsevier
Critical discoveries over the past two decades have transformed our understanding of
medulloblastoma from a single entity into a clinically and biologically heterogeneous …

Management of pediatric and adult patients with medulloblastoma

AM Martin, E Raabe, C Eberhart, KJ Cohen - Current treatment options in …, 2014 - Springer
Opinion Statement Approximately 70% of newly diagnosed children with medulloblastoma
(MB) will be classified as “standard risk”: their tumor is localized to the posterior fossa, they …

Recent developments and current concepts in medulloblastoma

NU Gerber, M Mynarek, K Von Hoff, C Friedrich… - Cancer treatment …, 2014 - Elsevier
Medulloblastoma is the most common malignant brain tumor of childhood. While prognosis
has significantly improved in the last decades with multimodal therapy including surgery …

EANO–EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma

E Franceschi, S Hofer, AA Brandes, D Frappaz… - The Lancet …, 2019 - thelancet.com
Summary The European Association of Neuro-Oncology (EANO) and EUropean RAre
CANcer (EURACAN) guideline provides recommendations for the diagnosis, treatment, and …

Updates on management of adult medulloblastoma

N Majd, M Penas-Prado - Current treatment options in oncology, 2019 - Springer
Opinion statement Medulloblastoma (MB) is a malignant embryonal tumor of the posterior
fossa and is the most common type of brain cancer in pediatric patients. In contrast, adult MB …

Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07)

D Beier, M Proescholdt, C Reinert, T Pietsch… - Neuro …, 2018 - academic.oup.com
Background Medulloblastoma in adult patients is rare, with 0.6 cases per million. Prognosis
depends on clinical factors and medulloblastoma entity. No prospective data on the …

Radiotherapy in medulloblastoma—evolution of treatment, current concepts and future perspectives

C Seidel, S Heider, P Hau, A Glasow, S Dietzsch… - Cancers, 2021 - mdpi.com
Simple Summary Craniospinal irradiation (CSI) is the backbone of medulloblastoma
treatment and the first treatment to achieve a cure in many patients. Within the last decades …

Chemotherapy increases long-term survival in patients with adult medulloblastoma—a literature-based meta-analysis

S Kocakaya, CP Beier, D Beier - Neuro-oncology, 2015 - academic.oup.com
Background Adult medulloblastoma is a potentially curable malignant entity with an
incidence of 0.5–1 per million. Valid data on prognosis, treatment, and demographics are …