Parenteral administration is one of the most commonly used drug delivery routes for
nanoparticle-based dosage forms, such as lipid-based and polymeric nanoparticles. For the …

Macrophages play vital functions in host inflammatory reaction, tissue repair, homeostasis
and immunity. Dysfunctional macrophages have significant pathophysiological impacts on …

The current work aims to explore the biological characteristics of vincristine synergistic co-
loading into pegylated liposomal doxorubicin in non-indicated modalities of non-small cell …

Aim: Chitosan-coated polylactic-co-glycolic acid nanoparticles of voriconazole (VChNP)
were developed to increase residence time and provide sustained drug release locally to …

Aspasomes of methotrexate with antioxidant, ascorbyl palmitate, were developed and
optimized using factorial design by varying parameters such as lipid molar ratio, drug to lipid …

Corticosteroids commonly prescribed in asthma show several side-effects. Relatively non-
toxic andrographolide (AG) has an anti-asthmatic potential. But its poor bioavailability and …

Liver cancer is a leading cause of death related to cancer worldwide. Poly (dl-lactide-co-
glycolide)(PLGA) nanoparticles provide prolonged blood residence time and sustained drug …

Purpose Herpes, a highly contagious viral infection caused by the herpes simplex virus,
infects the face to any other body part of the skin, even the genital areas. Among the anti …

Aim: To improve the efficacy of poly-ethylene glycol (PEG) ylated liposomes coloaded with
doxorubicin and vincristine against triple-negative breast cancer (TNBC) and non-small-cell …

Computational modelling has gained attention for evaluating nanoparticle-based drug
delivery systems. Physiologically based pharmacokinetic (PBPK) modelling provides a …