Psychedelics, also known as classical hallucinogens, have been investigated for decades
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …

Background: Research on psilocybin has become increasingly popular during the current
psychedelic renaissance, which began in the early 1990s. Psilocybin's effects on mental …

Background Psilocybin therapy (PT) produces rapid and persistent antidepressant effects in
major depressive disorder (MDD). However, the long-term effects of PT have never been …

Neural complexity correlates with one's level of consciousness. During coma, anesthesia,
and sleep, complexity is reduced. During altered states, including after lysergic acid …

BackgroundTo investigate the association between pre-trial expectancy, suggestibility, and
response to treatment in a trial of escitalopram and investigational drug, COMP360 …

Precision psychiatry aims to identify markers of interindividual variability that allow for
predicting the right treatment for each patient. However, bridging the gap between molecular …

Ethnopharmacology relevance Central nervous system (CNS) diseases can be diverse and
usually present with comorbidity, as in the case of depression and anxiety. Despite …

Background: In the wake of positive clinical trial outcomes of psychedelic-assisted
psychotherapy for the treatment of various psychiatric disorders, there has been an influx of …

Clinical trials of psychedelic compounds like psilocybin, LSD and DMT have forced a
reconsideration of how non-drug factors, like participant expectations, are measured and …

Alzheimer's disease (AD) stands as a formidable neurodegenerative ailment and a
prominent contributor to dementia. The scarcity of available therapies for AD accentuates the …