Apoptotic cell death in disease—Current understanding of the NCCD 2023
I Vitale, F Pietrocola, E Guilbaud… - Cell Death & …, 2023 - nature.com
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
Immunology of multiple sclerosis
M Sospedra, R Martin - Annu. Rev. Immunol., 2005 - annualreviews.org
▪ Abstract Multiple sclerosis (MS) develops in young adults with a complex predisposing
genetic trait and probably requires an inciting environmental insult such as a viral infection …
genetic trait and probably requires an inciting environmental insult such as a viral infection …
Overview of cell death signaling pathways
Z Jin, WS El-Deiry - Cancer biology & therapy, 2005 - Taylor & Francis
Apoptosis plays an important role in development and maintenance of tissue homeostasis.
Intensive efforts have been made to explore the molecular mechanisms of the apoptotic …
Intensive efforts have been made to explore the molecular mechanisms of the apoptotic …
The TRAIL apoptotic pathway in cancer onset, progression and therapy
RW Johnstone, AJ Frew, MJ Smyth - Nature Reviews Cancer, 2008 - nature.com
Triggering of tumour cell apoptosis is the foundation of many cancer therapies. Death
receptors of the tumour necrosis factor (TNF) superfamily have been largely characterized …
receptors of the tumour necrosis factor (TNF) superfamily have been largely characterized …
Apo2L/TRAIL and its death and decoy receptors
HN LeBlanc, A Ashkenazi - Cell Death & Differentiation, 2003 - nature.com
Apo2 ligand or tumour necrosis factor-related apoptosis-inducing ligand (Apo2L/TRAIL) is
one of the several members of the tumour necrosis factor (TNF) gene superfamily that …
one of the several members of the tumour necrosis factor (TNF) gene superfamily that …
Neutrophil apoptosis and the resolution of infection
AD Kennedy, FR DeLeo - Immunologic research, 2009 - Springer
Polymorphonuclear leukocytes (PMNs) are the most abundant white cell in humans and an
essential component of the innate immune system. PMNs are typically the first type of …
essential component of the innate immune system. PMNs are typically the first type of …
Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy
A Almasan, A Ashkenazi - Cytokine & growth factor reviews, 2003 - Elsevier
Apo2 ligand or tumor necrosis factor (TNF)-related apoptosis-inducing ligand (Apo2L/TRAIL)
is one of several members of the TNF gene superfamily that induce apoptosis through …
is one of several members of the TNF gene superfamily that induce apoptosis through …
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
E Cretney, K Takeda, H Yagita, M Glaccum… - The Journal of …, 2002 - journals.aai.org
We have previously implicated TNF-related apoptosis-inducing ligand (TRAIL) in innate
immune surveillance against tumor development. In this study, we describe the use of TRAIL …
immune surveillance against tumor development. In this study, we describe the use of TRAIL …
New insights into apoptosis signaling by Apo2L/TRAIL
F Gonzalvez, A Ashkenazi - Oncogene, 2010 - nature.com
Apoptosis ligand 2 tumor necrosis factor (TNF)-related apoptosis-inducing ligand
(Apo2L/TRAIL) belongs to a small subset of proapoptotic protein ligands in the TNF …
(Apo2L/TRAIL) belongs to a small subset of proapoptotic protein ligands in the TNF …
The multifaceted role of TRAIL signaling in cancer and immunity
L Cardoso Alves, N Corazza, O Micheau… - The FEBS …, 2021 - Wiley Online Library
Tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) is a member of the
TNF superfamily that can lead to the induction of apoptosis in tumor or infected cells …
TNF superfamily that can lead to the induction of apoptosis in tumor or infected cells …