Matrine: A review of its pharmacology, pharmacokinetics, toxicity, clinical application and preparation researches

X Li, Z Tang, L Wen, C Jiang, Q Feng - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance “Dogel ebs” was known as Sophora flavescens Ait., which
has been widely utilized in the clinical practice of traditional Chinese Mongolian herbal …

Research advances on matrine

XY Sun, LY Jia, Z Rong, X Zhou, LQ Cao, AH Li… - Frontiers in …, 2022 - frontiersin.org
Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora
flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of …

Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives

HI Abd-Alla, D Souguir, MO Radwan - Archives of pharmacal research, 2021 - Springer
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third
largest family of flowering plants. The genus Sophora comprises approximately 52 species …

Natural products in preventing tumor drug resistance and related signaling pathways

C Yang, Z Mai, C Liu, S Yin, Y Cai, C Xia - Molecules, 2022 - mdpi.com
Drug resistance is still an obstacle in cancer therapy, leading to the failure of tumor
treatment. The emergence of tumor drug resistance has always been a main concern of …

Matrine exerts pharmacological effects through multiple signaling pathways: a comprehensive review

Y Lin, F He, L Wu, Y Xu, Q Du - Drug Design, Development and …, 2022 - Taylor & Francis
As The main effective monomer of the traditional Chinese medicine Sophora flavescens Ait,
matrine has a broad scope of pharmacological activities such as anti-tumor, anti …

Biological activity of naturally derived naphthyridines

G Chabowska, E Barg, A Wójcicka - Molecules, 2021 - mdpi.com
Marine and terrestrial environments are rich sources of various bioactive substances, which
have been used by humans since prehistoric times. Nowadays, due to advances in chemical …

A review on phytochemicals as combating weapon for multidrug resistance in cancer

S Gupta, A Mehra, R Sangwan - Journal of Asian Natural Products …, 2024 - Taylor & Francis
One can recognize multidrug resistance (MDR) and residue as a biggest difficulty in cancer
specialist. Chemotherapy-resistant cancer may be successfully treated by combining MDR …

Design, synthesis, molecular docking, and tumor resistance reversal activity evaluation of matrine derivative with thiophene structure

J Wei, Y Liang, L Wu - Molecules, 2021 - mdpi.com
Nasopharyngeal carcinoma (NPC) frequently occurs in Southern China. The main
treatments of NPC are chemotherapy and radiotherapy. However, chemo-resistance arises …

[HTML][HTML] Compound kushen injection in cancer treatments: Efficacy, active ingredients, and mechanisms

Y Yang, Y Lu, T Pei, B Guo, J Li, H Wang… - … Research-Modern Chinese …, 2022 - Elsevier
Cancer remains a major cause of death and a severe threat to improve life span around the
world. Although the cancer treatments have made great progress, the therapeutic outcomes …

Profiling and quantitation of alkaloids in different parts of Sophora alopecuroides L. extracts by high‐performance liquid chromatography with electrospray ionisation …

X Jia, H Zhang, X Jiang, Y Lu, W Liu… - Phytochemical …, 2021 - Wiley Online Library
Introduction Ambient pressure electrospray ionisation ion mobility spectrometry coupled to
high‐performance liquid chromatography (HPLC) was used to detect alkaloids from different …