Testicular cancer is the most common malignancy among men between 14 and 44 years of
age, and its incidence has risen over the past two decades in Western countries. Both …

Aberrant glycans are a hallmark of cancer states. Notably, emerging evidence has
demonstrated that the diagnosis of cancers with tumour-specific glycan patterns holds great …

PURPOSE Previous studies suggested that serum levels of microRNA (miR)-371a-3p (so-
called M371 test) have a much higher sensitivity and specificity than the classic markers of …

Testicular tumors are the most common tumors in adolescent and young men and germ cell
tumors (TGCTs) account for most of all testicular cancers. Increasing incidence of TGCTs …

PURPOSE Our objective was to evaluate operating characteristics, particularly specificity
and positive predictive value (PPV), by mapping plasma miR371 expression to actual …

Introduction. Although serum tumor markers beta human chorionic gonadotropin (bHCG),
alpha‐fetoprotein (AFP), and lactate dehydrogenase (LDH) are well‐established tools for …

Testicular germ cell tumours (TGCTs) are the most frequent cancer type in young men and
originate from the common precursor germ cell neoplasia in situ (GCNIS). For decades …

Abstract Rationale: PIWI-interacting RNAs (piRNAs), a class of newly discovered small RNA
molecules that function by binding to the Argonaute protein family (ie, the PIWIL protein …

The glycosylation pattern of alpha fetoprotein (AFP) paves the basis for precise early
diagnosis of hepatocellular carcinoma (HCC). However, existing analytical methods ignore …

Extracellular vesicles (EVs) are nano-sized particles that hold tremendous potential in the
clinical space, as their biomolecular profiles hold a key to non-invasive liquid biopsy for …