State dependent vagus nerve stimulation for targeted plasticity therapy: challenges and considerations

B Nandakumar, RV Mylavarapu, R Harris… - Frontiers in Control …, 2024 - frontiersin.org
Targeted plasticity therapy (TPT) utilizes vagus nerve stimulation (VNS) to promote
improvements in function following neurological injury and disease. During TPT, a brief burst …

Exercise therapy guides cortical reorganization after midthoracic spinal contusion to enhance control of lower thoracic muscles, supporting functional recovery

B Nandakumar, GH Blumenthal, GD Disse… - Experimental …, 2023 - Elsevier
Postural control is critical for locomotion, allowing for gait changes, obstacle avoidance and
navigation of rough terrain. A major problem after spinal cord injury (SCI) is regaining the …

Hindlimb somatosensory information influences trunk sensory and motor cortices to support trunk stabilization

B Nandakumar, GH Blumenthal, FP Pauzin… - Cerebral …, 2021 - academic.oup.com
Sensorimotor integration in the trunk system is poorly understood despite its importance for
functional recovery after neurological injury. To address this, a series of mapping studies …

Corticothalamic input derived from corticospinal neurons contributes to chronic neuropathic pain after spinal cord injury

L Liu, Z Liang, L Zhang, Z Feng, F Cao, Y Zhang… - Experimental …, 2024 - Elsevier
Neuropathic pain is a significant and persistent issue for individuals with spinal cord injuries
(SCI), severely impacting their quality of life. While changes at the peripheral and spinal …

[HTML][HTML] The relationship between changes in inflammation and locomotor function in sensory phenotypes of central neuropathic pain after spinal cord injury

BL Avonts, Q Shen, NJ Wrobel, RG Fessler… - Pain …, 2024 - journals.lww.com
Objective: To investigate the physiological processes contributing to neuropathic pain
sensory changes and locomotor impairments with sensory phenotypes that develop over …

[HTML][HTML] Comprehensive phenotyping of cutaneous afferents reveals early-onset alterations in nociceptor response properties, release of CGRP, and hindpaw edema …

OC Eller, RN Stair, C Neal, PSN Rowe… - Neurobiology of Pain, 2022 - Elsevier
Spinal cord injury (SCI) is a complex syndrome that has profound effects on patient well-
being, including the development of medically-resistant chronic pain. The mechanisms …

[图书][B] Somatosensory Cortex Undergoes Maladaptive Reorganization with Neuropathic Pain Development after Spinal Cord Injury

GH Blumenthal - 2021 - search.proquest.com
Spinal cord injury (SCI) is a severely debilitating condition that affects millions of individuals
worldwide. A common complication after SCI is the development of chronic neuropathic …

[图书][B] Role of Trunk Sensorimotor Cortex in Supporting Rehabilitation Assisted Functional Recovery of Locomotion after Spinal Contusion Injury

B Nandakumar - 2021 - search.proquest.com
Spinal cord injury (SCI) is a debilitating condition often resulting in motor deficits and loss of
tactile sensation below the injury. The brain needs to relearn strategies to regain motor …

[引用][C] Eggs or peanuts in early infant diet may cut allergy risk

J Wise - 2016 - bmj.com
Spinal cord injury (SCI) is a complex syndrome that has profound effects on patient well-
being, including the development of medically-resistant chronic pain. The mechanisms …