Amides are versatile building blocks in synthetic organic chemistry, presenting a wide range
of pharmacological applications, and are used as raw materials in industry for the large …

Secondary phosphine oxides present tautomeric equilibrium between the pentavalent oxide
form (SPO) and the trivalent phosphinous acid (PA). This dichotomy is the origin of the rich …

A simple, mild and general procedure for the hydration of nitriles to amides using copper as
catalyst and promoted by N, N-diethylhydroxylamine is described. The reaction can be …

The hydration of nitriles is an atom economical route to generate primary amides of great
academic and industrial significance. From an academic perspective, considerable progress …

Nitrile hydration provides access to amides that are indispensable to researchers in
chemical and pharmaceutical industries. Prohibiting the use of this venerable reaction …

A series of water-soluble N-protonated thiazolyl-phosphine hydrochloride salts have been
synthesized and coordinated to the ruthenium (II) fragment [RuCl2 (η6-p-cymene)]. The …

The transition metal-catalyzed hydration of nitriles is an efficient route to amides, which are
important synthetic building blocks. Many heterogeneous and homogeneous catalysts have …

The NiII complex 1 containing pyridyl‐and hydroxy‐functionalized N‐heterocyclic carbenes
(NHCs) is synthesized and its catalytic utility for the selective nitrile hydration to the …

Treatment of [Rh (COD)(μ-Cl)] 2 with excess t BuOK and subsequent addition of 2 equiv of
PIN· HBr in THF afforded [Rh (COD)(κC2-PIN) Br](1)(PIN= 1-isopropyl-3-(5, 7-dimethyl-1, 8 …

The catalytic hydration of benzonitrile and acetonitrile has been studied by employing
different arene–ruthenium (II) complexes with phosphinous (PR2OH) and phosphorous acid …