Gut microbiota has implications in Central Nervous System (CNS) disorders. Our study
systematically identified preclinical studies aimed to investigate the possible gut microbiota …

Chronic pain remains one of the world's most persistent and unsolved clinical challenges
that severely affect patients' quality of life. Presently, considering that the mechanisms …

Zingiber officinale and Panax ginseng, as well-known traditional Chinese medicines, have
been used together to clinically treat ulcerative colitis with synergistic effects for thousands of …

Purpose To explore the potential therapeutic strategies of different types of neuropathic pain
(NP) and to summarize the cutting-edge novel approaches for NP treatment based on the …

Brown goat milk products have gained popularity for their unique taste and flavor. The
emergence of chain-reversal phenomenon makes the design and development of goat milk …

Sea cucumber peptides have been proven to exhibit a variety of biological activities.
Ulcerative colitis (UC) is a chronic disease characterized by diffuse inflammation of the …

Chlorogenic acid (CGA) and epigallocatechin-3-gallate (EGCG) are major polyphenolic
constituents of coffee and green tea with beneficial health properties. In this study, we …

Rheumatoid arthritis (RA) is an inflammatory-mediated autoimmune disease characterized
by persistent joint enlargement, synovial cartilage damage, and inflammatory infiltrates …

Purpose Paclitaxel-induced peripheral neuropathy (PIPN) constitutes a refractory and
progressive adverse consequence of paclitaxel treatment, causing pain and sensory …

Background Emerging research suggests hyperglycemia can increase intestinal
permeability. Ginger and its bioactive compounds have been reported to benefit diabetic …