Kindling and status epilepticus models of epilepsy: rewiring the brain
K Morimoto, M Fahnestock, RJ Racine - Progress in neurobiology, 2004 - Elsevier
This review focuses on the remodeling of brain circuitry associated with epilepsy, particularly
in excitatory glutamate and inhibitory GABA systems, including alterations in synaptic …
in excitatory glutamate and inhibitory GABA systems, including alterations in synaptic …
Cyclooxygenase-2 (COX-2) inhibitors: future therapeutic strategies for epilepsy management
Epilepsy, a common multifactorial neurological disease, affects about 69 million people
worldwide constituting nearly 1% of the world population. Despite decades of extensive …
worldwide constituting nearly 1% of the world population. Despite decades of extensive …
Blood–brain barrier leakage may lead to progression of temporal lobe epilepsy
EA Van Vliet, S da Costa Araújo, S Redeker… - Brain, 2007 - academic.oup.com
Leakage of the blood–brain barrier (BBB) is associated with various neurological disorders,
including temporal lobe epilepsy (TLE). However, it is not known whether alterations of the …
including temporal lobe epilepsy (TLE). However, it is not known whether alterations of the …
Prevention or modification of epileptogenesis after brain insults: experimental approaches and translational research
Diverse brain insults, including traumatic brain injury, stroke, infections, tumors,
neurodegenerative diseases, and prolonged acute symptomatic seizures, such as complex …
neurodegenerative diseases, and prolonged acute symptomatic seizures, such as complex …
Blood–brain barrier dysfunction, seizures and epilepsy
EA Van Vliet, E Aronica, JA Gorter - Seminars in cell & Developmental …, 2015 - Elsevier
The blood–brain barrier (BBB) is a dynamic and complex system which separates the brain
from the blood. It helps to maintain the homeostasis of the brain, which is essential for …
from the blood. It helps to maintain the homeostasis of the brain, which is essential for …
Blood–brain barrier dysfunction and epilepsy: pathophysiologic role and therapeutic approaches
The blood–brain barrier (BBB) is located within a unique anatomic interface and has
functional ramifications to most of the brain and blood cells. In the past, the BBB was …
functional ramifications to most of the brain and blood cells. In the past, the BBB was …
Status epilepticus, blood–brain barrier disruption, inflammation, and epileptogenesis
JA Gorter, EA van Vliet, E Aronica - Epilepsy & Behavior, 2015 - Elsevier
Over the last 15 years, attention has been focused on dysfunction of the cerebral vasculature
and inflammation as important players in epileptogenic processes, with a specific emphasis …
and inflammation as important players in epileptogenic processes, with a specific emphasis …
Cyclooxygenase‐2 in epilepsy
Epilepsy is one of the more prevalent neurologic disorders in the world, affecting
approximately 50 million people of different ages and backgrounds. Epileptic seizures …
approximately 50 million people of different ages and backgrounds. Epileptic seizures …
Temporal lobe sclerosis associated with hippocampal sclerosis in temporal lobe epilepsy: neuropathological features
M Thom, S Eriksson, L Martinian… - … of Neuropathology & …, 2009 - academic.oup.com
Widespread changes involving neocortical and mesial temporal lobe structures can be
present in patients with temporal lobe epilepsy and hippocampal sclerosis. The incidence …
present in patients with temporal lobe epilepsy and hippocampal sclerosis. The incidence …
Association of piriform cortex resection with surgical outcomes in patients with temporal lobe epilepsy
Importance A functional area associated with the piriform cortex, termedarea tempestas, has
been implicated in animal studies as having a crucial role in modulating seizures, but similar …
been implicated in animal studies as having a crucial role in modulating seizures, but similar …