[HTML][HTML] Cytotoxic activity of the genus Ferula (Apiaceae) and its bioactive constituents

M Iranshahi, R Rezaee, MN Najafi… - Avicenna Journal of …, 2018 - ncbi.nlm.nih.gov
Objective: The genus Ferula L. includes perennial flowering plants belonging to the
Apiaceae family. This genus is a rich source of biologically active phytochemicals such as …

Recent advances on bioactive constituents in Ferula

Y Zhou, F Xin, G Zhang, H Qu… - Drug development …, 2017 - Wiley Online Library
ABSTRACT Preclinical Research The genus Ferula (Umbelliferea) is widely distributed
across Central Asia and the Mediterranean. Some plants of the genus Ferula have been …

Antioxidant and anticholinesterase potential of diterpenoid alkaloids from Aconitum heterophyllum

H Ahmad, S Ahmad, SAA Shah, A Latif, M Ali… - Bioorganic & medicinal …, 2017 - Elsevier
Extensive chromatographic separations performed on the basic (pH= 8–10) chloroform
soluble fraction of Aconitum heterophyllum resulted in the isolation of three new diterpenoid …

Norditerpenoid alkaloids of Delphinium denudatum as cholinesterase inhibitors

H Ahmad, S Ahmad, M Ali, A Latif, SAA Shah, H Naz… - Bioorganic …, 2018 - Elsevier
Three new norditerpenoids alkaloids, 1β-hydroxy, 14β-acetyl condelphine (1), jadwarine-A
(2), jadwarine-B (3) along with two known alkaloids isotalatizidine hydrate (4) and …

Isolation, crystal structure determination and cholinesterase inhibitory potential of isotalatizidine hydrate from Delphinium denudatum

H Ahmad, S Ahmad, E Khan, A Shahzad… - Pharmaceutical …, 2017 - Taylor & Francis
Abstract Context: Delphinium denudatum Wall (Ranunculaceae) is a rich source of
diterpenoid alkaloids and is widely used for the treatment of various neurological disorders …

Computer‐aided Evaluation of Polyvalent Medications' Pharmacological Potential. Multiphytoadaptogen as a Case Study

OA Bocharova, NS Ionov, IV Kazeev… - Molecular …, 2023 - Wiley Online Library
Many human diseases including cancer, degenerative and autoimmune disorders, diabetes
and others are multifactorial. Pharmaceutical agents acting on a single target do not provide …

[HTML][HTML] Gummosin, a sesquiterpene coumarin from Ferula assa-foetida is preferentially cytotoxic to human breast and prostate cancer cell lines

M Iranshahy, F Farhadi, B Paknejad… - Avicenna Journal of …, 2019 - ncbi.nlm.nih.gov
Objective: The present study was conducted to find cytotoxic compounds from oleo-gum-
resin of Ferula assa-foetida (asafoetida). Materials and Methods: A dichloromethane extract …

Computer-aided drug design applied to secondary metabolites as anticancer agents

RSA de Araújo, EF da Silva-Junior… - Current Topics in …, 2020 - ingentaconnect.com
Computer-Aided Drug Design (CADD) techniques have garnered a great deal of attention in
academia and industry because of their great versatility, low costs, possibilities of cost …

GC-MS Analysis, Metal Analysis and Antimicrobial Investigation of Sterculia diversifolia

F Rabbi, A Zada, A Adhikari, A Nisar, FU Khan… - Pharmaceutical …, 2020 - Springer
Plants of Sterculia genus contain various types of bioactive compounds which bears
therapeutic potential. The current research was planned to perform gas chromatography …

Isolation, crystal structure, DFT calculation and molecular docking of uncinatine-A isolated from Delphinium uncinatum

S Ahmad, N Gul, M Ahmad, M Almehmadi, A Shafie… - Fitoterapia, 2022 - Elsevier
The main objective of our present research work was to explore molecular insight for
potentially active new acetylcholinesterase inhibitor from the aerial parts of Delphinium …