The incidence of hepatocellular carcinoma (HCC) has been rising worldwide over the last
20 years and is expected to increase until 2030 in some countries including the United …

Hepatitis B virus (HBV) contributes to hepatocellular carcinoma (HCC) development through
direct and indirect mechanisms. HBV DNA integration into the host genome occurs at early …

中国人群的肝癌存在生存率低, 死亡率高的情况, 如何有效降低肝癌相关负担仍是中国公共卫生
和慢性病防控领域亟待解决的重大问题, 而肝癌人群筛查策略优化是值得持续探索的重要抓手和 …

We investigated the clinical significance of a vascular growth pattern of hepatocellular
carcinoma (HCC), the vessels that encapsulate tumor clusters (VETC), previously linked to …

Objectives To develop and validate a pre-transcatheter arterial chemoembolization (TACE)
MRI-based radiomics model for predicting tumor response in intermediate-advanced …

Knowledge of the fundamental epigenetic mechanisms governing gene expression and
cellular phenotype are sufficiently advanced that novel insights into the epigenetic control of …

Please see the Editorial Comment by Antonio Luna discussing this article. The 2019 5th
edition of the WHO classification of digestive system tumors estimates that up to 35% of …

Purpose: The impact of tertiary lymphoid structures (TLS) in hepatocellular carcinoma (HCC)
progression is being extensively investigated. However, their presence during the early …

Histopathologists retain a critical role in the diagnosis and management of hepatocellular
carcinoma (HCC). HCC arises usually but not exclusively in a background of advanced …

Hepatocellular carcinoma (HCC) is one of the most common solid tumor malignancies in the
world and represents roughly 90% of all primary malignancies of the liver. The most …