The lineage transition between epithelium and mesenchyme is a process known as
epithelial–mesenchymal transition (EMT), by which polarized epithelial cells lose their …

The function of the mammalian heart depends on the interplay between different cardiac cell
types. The deployment of these cells, with precise spatiotemporal regulation, is also …

Our understanding of the functions of cardiac fibroblasts has moved beyond their roles in
heart structure and extracellular matrix generation and now includes their contributions to …

The heart is lined by a single layer of mesothelial cells called the epicardium that provides
important cellular contributions for embryonic heart formation. The epicardium harbors a …

Epithelial-mesenchymal transition (EMT) is a crucial, evolutionarily conserved process that
occurs during development and is essential for shaping embryos. Also implicated in cancer …

The epithelial to mesenchymal transition (EMT) converts epithelial cells into migratory and
invasive cells and is a fundamental event in morphogenesis. Although its relevance in the …

The presence of ribonucleotides in genomic DNA is undesirable given their increased
susceptibility to hydrolysis. Ribonuclease (RNase) H enzymes that recognize and process …

Epithelial to mesenchymal transition (EMT) converts epithelial cells to mobile and
developmentally plastic mesenchymal cells. All cells in the heart arise from one or more …

Cellular switching from an epithelial-to-mesenchymal phenotype, and conversely from a
mesenchymal-toepithelial phenotype, are important biological programs that are operative …

Fuelled by the obesity epidemic, there is considerable interest in the developmental origins
of white adipose tissue (WAT) and the stem and progenitor cells from which it arises …