[HTML][HTML] Modern isolation and separation techniques for extracellular vesicles

T Liangsupree, E Multia, ML Riekkola - Journal of Chromatography A, 2021 - Elsevier
Extracellular vesicles (EVs) are heterogenous membrane-bound vesicles released from
various origins. EVs play a crucial role in cellular communication and mediate several …

[HTML][HTML] Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications

Y Jia, L Yu, T Ma, W Xu, H Qian, Y Sun, H Shi - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as
important messengers in cell-to-cell communication and as a promising drug delivery …

[HTML][HTML] Extracellular vesicles as drug delivery systems: Why and how?

OM Elsharkasy, JZ Nordin, DW Hagey… - Advanced drug delivery …, 2020 - Elsevier
Over the past decades, a multitude of synthetic drug delivery systems has been developed
and introduced to the market. However, applications of such systems are limited due to …

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …

C Théry, KW Witwer, E Aikawa… - Journal of …, 2018 - Wiley Online Library
The last decade has seen a sharp increase in the number of scientific publications
describing physiological and pathological functions of extracellular vesicles (EVs), a …

A review on comparative studies addressing exosome isolation methods from body fluids

TS Martins, M Vaz, AG Henriques - Analytical and Bioanalytical Chemistry, 2023 - Springer
Exosomes emerged as valuable sources of disease biomarkers and new therapeutic tools.
However, extracellular vesicles isolation with exosome-like characteristics from certain …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Extracellular vesicle heterogeneity and its impact for regenerative medicine applications

SI Van De Wakker, FM Meijers, JPG Sluijter… - Pharmacological …, 2023 - Elsevier
Extracellular vesicles (EVs) are cell-derived membrane-enclosed particles that are involved
in physiologic and pathologic processes. EVs are increasingly being studied for therapeutic …

Manufacturing exosomes: a promising therapeutic platform

IL Colao, R Corteling, D Bracewell, I Wall - Trends in molecular medicine, 2018 - cell.com
Extracellular vesicles, in particular the subclass exosomes, are rapidly emerging as a novel
therapeutic platform. However, currently very few clinical validation studies and no clearly …

[HTML][HTML] Manufacturing therapeutic exosomes: from bench to industry

SH Ahn, SW Ryu, H Choi, S You, J Park, C Choi - Molecules and cells, 2022 - Elsevier
Exosome, a type of nanoparticles also known as small extracellular vesicles are gaining
attention as novel therapeutics for various diseases because of their ability to deliver genetic …

Extracellular signals regulate the biogenesis of extracellular vesicles

Y Jin, L Ma, W Zhang, W Yang, Q Feng, H Wang - Biological Research, 2022 - Springer
Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of
proteins and RNAs for intercellular communication. With various biomolecules and specific …