Ginseng has gained its popularity as an adaptogen since ancient days because of its
triterpenoid saponins, known as ginsenosides. These triterpenoid saponins are unique and …

Objective Wnt signaling pathway significantly participates in cardiac fibrosis and CFs
activation. Therefore, we reviewed current evidence on the new perspectives and biological …

Abstract Background Ginsenoside Rg3 (Rg3), one of the most potent components extracted
from the roots of the traditional Chinese herb Panax ginseng, has prominent roles in anti …

Ginsenoside Rg1, a saponin that is a primary component of ginseng, has been
demonstrated to protect hearts from diverse cardiovascular diseases with regulating multiple …

Abstract The Chinese medicinal plant Panax notoginseng has been traditionally used to
activate blood flow and circulation, and to prevent blood stasis. P. notoginseng contains …

Introduction Anti-oxidative stress and inhibition of TGF-β1/Smads signaling cascade are
essential therapeutic strategies for diabetic nephropathy (DN). In this study, we aimed to …

Cardiovascular disease (CVD) remains the major cause of death worldwide, accounting for
almost 31% of the global mortality annually. Several preclinical studies have indicated that …

Cardiac hypertrophy is a maladaptive change in response to pressure overload, and is also
an important risk for developing heart failure. Berberine is known to have cardioprotective …

Coronary heart disease (CHD) is the most common clinical manifestation of cardiovascular
disease. It is characterized by myocardial ischemia, which is caused by coronary …

Ginsenoside Rg1 has been demonstrated to have cardiovascular protective effects.
However, whether the cardioprotective effects of ginsenoside Rg1 are mediated by …