Immune-microbe interactions early in life: A determinant of health and disease long term
P Brodin - Science, 2022 - science.org
Research on newborn immunity has revealed the importance of cell ontogeny, feto-maternal
tolerance, and the transfer of maternal antibodies. Less is known about postnatal adaptation …
tolerance, and the transfer of maternal antibodies. Less is known about postnatal adaptation …
Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms
The need for highly effective vaccines that induce robust and long-lasting immunity has
never been more apparent. However, for reasons that are still poorly understood, immune …
never been more apparent. However, for reasons that are still poorly understood, immune …
[HTML][HTML] Gut microbiota composition is associated with SARS-CoV-2 vaccine immunogenicity and adverse events
Objective The gut microbiota plays a key role in modulating host immune response. We
conducted a prospective, observational study to examine gut microbiota composition in …
conducted a prospective, observational study to examine gut microbiota composition in …
Control of immunity by the microbiota
The immune system has coevolved with extensive microbial communities living on barrier
sites that are collectively known as the microbiota. It is increasingly clear that microbial …
sites that are collectively known as the microbiota. It is increasingly clear that microbial …
Indole-3-lactic acid associated with Bifidobacterium-dominated microbiota significantly decreases inflammation in intestinal epithelial cells
Background Bifidobacterium longum subsp. infantis (B. infantis) is a commensal bacterium
that colonizes the gastrointestinal tract of breast-fed infants. B. infantis can efficiently utilize …
that colonizes the gastrointestinal tract of breast-fed infants. B. infantis can efficiently utilize …
Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis
Aside from centrally induced trained immunity in the bone marrow (BM) and peripheral
blood by parenteral vaccination or infection, evidence indicates that mucosal-resident innate …
blood by parenteral vaccination or infection, evidence indicates that mucosal-resident innate …
Memory T cells: strategies for optimizing tumor immunotherapy
Q Liu, Z Sun, L Chen - Protein & cell, 2020 - academic.oup.com
Several studies have demonstrated that memory T cells including stem cell memory (Tscm)
T cells and central memory (Tcm) T cells show superior persistence and antitumor immunity …
T cells and central memory (Tcm) T cells show superior persistence and antitumor immunity …
[HTML][HTML] A distinct clade of Bifidobacterium longum in the gut of Bangladeshi children thrives during weaning
The gut microbiome has an important role in infant health and development. We
characterized the fecal microbiome and metabolome of 222 young children in Dhaka …
characterized the fecal microbiome and metabolome of 222 young children in Dhaka …
[HTML][HTML] The impact of the microbiome on immunity to vaccination in humans
Vaccines are the most effective means available for preventing infectious diseases.
However, vaccine-induced immune responses are highly variable between individuals and …
However, vaccine-induced immune responses are highly variable between individuals and …
Intestinal 'infant-type'bifidobacteria mediate immune system development in the first 1000 days of life
C Lin, Y Lin, H Zhang, G Wang, J Zhao, H Zhang… - Nutrients, 2022 - mdpi.com
Immune system maturation begins early in life, but few studies have examined how early-life
gut microbiota colonization educates the neonatal immune system. Bifidobacteria …
gut microbiota colonization educates the neonatal immune system. Bifidobacteria …