Mechanisms of key innate immune cells in early-and late-onset preeclampsia
I Aneman, D Pienaar, S Suvakov, TP Simic… - Frontiers in …, 2020 - frontiersin.org
Preeclampsia is a complex cardiovascular disorder of pregnancy with underlying
multifactorial pathogeneses; however, its etiology is not fully understood. It is characterized …
multifactorial pathogeneses; however, its etiology is not fully understood. It is characterized …
B cell development and maturation
Y Wang, J Liu, PD Burrows, JY Wang - B Cells in Immunity and Tolerance, 2020 - Springer
Since the identification of B cells in 1965 (Cooper et al. 1965), three has been tremendous
progress in our understanding of B cell development, maturation and function. A number of …
progress in our understanding of B cell development, maturation and function. A number of …
Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70−
DO Griffin, NE Holodick, TL Rothstein - Journal of Experimental …, 2011 - rupress.org
B1 cells differ in many ways from conventional B cells, most prominently in the production of
natural immunoglobulin, which is vitally important for protection against pathogens. B1 cells …
natural immunoglobulin, which is vitally important for protection against pathogens. B1 cells …
Specialized immune responses in the peritoneal cavity and omentum
M Liu, A Silva-Sanchez, TD Randall… - Journal of Leucocyte …, 2021 - academic.oup.com
The peritoneal cavity is a fluid filled space that holds most of the abdominal organs,
including the omentum, a visceral adipose tissue that contains milky spots or clusters of …
including the omentum, a visceral adipose tissue that contains milky spots or clusters of …
Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment
A lot of effort has been done to study how cancer cells react to low-oxygen tension, a
condition known as hypoxia. Indeed, abnormal and dysfunctional blood vessels in the tumor …
condition known as hypoxia. Indeed, abnormal and dysfunctional blood vessels in the tumor …
Phenotypic and functional heterogeneity of human memory B cells
Memory B cells are more heterogeneous than previously thought. Given that B cells play
powerful antibody-independent effector functions, it seems reasonable to assume division of …
powerful antibody-independent effector functions, it seems reasonable to assume division of …
A novel IL-10–independent regulatory role for B cells in suppressing autoimmunity by maintenance of regulatory T cells via GITR ligand
B cells are important for the regulation of autoimmune responses. In experimental
autoimmune encephalomyelitis (EAE), B cells are required for spontaneous recovery in …
autoimmune encephalomyelitis (EAE), B cells are required for spontaneous recovery in …
Human B‐1 cells take the stage
TL Rothstein, DO Griffin, NE Holodick… - Annals of the New …, 2013 - Wiley Online Library
B‐1 cells play critical roles in defending against microbial invasion and in housekeeping
removal of cellular debris. B‐1 cells secrete natural antibody and manifest functions that …
removal of cellular debris. B‐1 cells secrete natural antibody and manifest functions that …
Helminth infections associated with multiple sclerosis induce regulatory B cells
J Correale, M Farez, G Razzitte - Annals of Neurology: Official …, 2008 - Wiley Online Library
Objective To assess the importance of B‐cell control during parasite infections in multiple
sclerosis (MS) patients. Methods Peripheral blood CD19+ B cells from 12 helminth‐infected …
sclerosis (MS) patients. Methods Peripheral blood CD19+ B cells from 12 helminth‐infected …
B cells as therapeutic targets in SLE
The use of B-cell targeted therapies for the treatment of systemic lupus erythematosus (SLE)
has generated great interest owing to the multiple pathogenic roles carried out by B cells in …
has generated great interest owing to the multiple pathogenic roles carried out by B cells in …