Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …

B cells represent a relatively minor cell population within both the healthy and diseased
central nervous system (CNS), yet they can have profound effects. This is emphasized in …

The balance between immune effector cells and immunosuppressive cells and how this
regulates the tumor microenvironment has been well described. A significant contribution of …

Allergy is a major public health problem with a high socio‐economic impact. The number of
allergic patients is expected to reach to four billion within two decades when the World's …

In the tumor microenvironment (TME), tumor cells are constantly evolving to reduce
neoantigen generation and the mutational burden to escape the anti-tumor response. This …

During malignant transformation, accumulated somatic mutations endow cancer cells with
increased invasiveness and immunogenicity. Under selective pressure, these highly …

Our understanding of tumor-infiltrating lymphocytes (TILs) is rapidly expanding beyond T cell-
centric perspectives to include B cells and plasma cells, collectively referred to as TIL-Bs. In …

Cancer cells develop mechanisms to escape immunosurveillance, among which modulating
the expression of immune suppressive messenger RNAs is most well-documented …

Immune dysregulation is a cardinal feature of chronic lymphocytic leukemia (CLL) from its
early stage and worsens during clinical observation, even in absence of disease …

Recent years have seen a renaissance in the research linking inflammation and cancer with
immune cells playing a central role in smouldering inflammation in the tumor …