Syphilis

RW Peeling, D Mabey, ML Kamb… - Nature reviews …, 2017 - pmc.ncbi.nlm.nih.gov
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure
or vertical transmission during pregnancy. T. pallidum is renowned for its invasiveness and …

Syphilis in pregnancy

EH Adhikari - Obstetrics & Gynecology, 2020 - journals.lww.com
Syphilis in Pregnancy : Obstetrics & Gynecology Syphilis in Pregnancy : Obstetrics &
Gynecology ACOG.org ACOG Clinical Green Journal For Patients Store Log in or Register …

Treponema pallidum genome sequencing from six continents reveals variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar

NAP Lieberman, MJ Lin, H Xie, L Shrestha… - PLoS neglected …, 2021 - journals.plos.org
In spite of its immutable susceptibility to penicillin, Treponema pallidum (T. pallidum) subsp.
pallidum continues to cause millions of cases of syphilis each year worldwide, resulting in …

A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples

W Chen, H Luo, L Zeng, Y Pan, JB Parr, Y Jiang… - Nature …, 2022 - nature.com
The performance of commonly used assays for diagnosis of syphilis varies considerably
depending on stage of infection and sample type. In response to the need for improved …

[HTML][HTML] Ancient bacterial genomes reveal a high diversity of Treponema pallidum strains in early modern Europe

K Majander, S Pfrengle, A Kocher, J Neukamm… - Current Biology, 2020 - cell.com
Syphilis is a globally re-emerging disease, which has marked European history with a
devastating epidemic at the end of the 15 th century. Together with non-venereal treponemal …

Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis

MA Beale, M Marks, MJ Cole, MK Lee, R Pitt… - Nature …, 2021 - nature.com
Syphilis, which is caused by the sexually transmitted bacterium Treponema pallidum subsp.
pallidum, has an estimated 6.3 million cases worldwide per annum. In the past ten years, the …

Evolutionary Processes in the Emergence and Recent Spread of the Syphilis Agent, Treponema pallidum

M Pla-Diaz, L Sánchez-Busó, L Giacani… - Molecular biology …, 2022 - academic.oup.com
The incidence of syphilis has risen worldwide in the last decade in spite of being an easily
treated infection. The causative agent of this sexually transmitted disease is the bacterium …

Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages

MA Beale, M Marks, SK Sahi, LC Tantalo… - Nature …, 2019 - nature.com
Syphilis is a sexually transmitted infection caused by Treponema pallidum subspecies
pallidum and may lead to severe complications. Recent years have seen striking increases …

Molecular characterization of Treponema pallidum subsp. pallidum in Switzerland and France with a new multilocus sequence typing scheme

L Grillová, T Bawa, L Mikalova, A Gayet-Ageron… - PloS one, 2018 - journals.plos.org
Syphilis is an important public health problem and an increasing incidence has been noted
in recent years. Characterization of strain diversity through molecular data plays a critical …

Contaminant DNA in bacterial sequencing experiments is a major source of false genetic variability

GA Goig, S Blanco, AL Garcia-Basteiro, I Comas - BMC biology, 2020 - Springer
Background Contaminant DNA is a well-known confounding factor in molecular biology and
in genomic repositories. Strikingly, analysis workflows for whole-genome sequencing (WGS) …