New perspectives on biology, disease progression, and therapy response of head and neck cancer gained from single cell RNA sequencing and spatial …

G Heller, T Fuereder, AM Grandits… - Oncology …, 2023 - pmc.ncbi.nlm.nih.gov
Head and neck squamous cell carcinoma (HNSCC) is one of the most frequent cancers
worldwide. The main risk factors are consumption of tobacco products and alcohol, as well …

Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones

A Ianevski, K Nader, K Driva, W Senkowski… - Nature …, 2024 - nature.com
Intratumoral cellular heterogeneity necessitates multi-targeting therapies for improved
clinical benefits in advanced malignancies. However, systematic identification of patient …

Spatial transcriptomics in glioblastoma: is knowing the right zip code the key to the next therapeutic breakthrough?

JM Shireman, L Cheng, A Goel, DM Garcia… - Frontiers in …, 2023 - frontiersin.org
Spatial transcriptomics, the technology of visualizing cellular gene expression landscape in
a cells native tissue location, has emerged as a powerful tool that allows us to address …

The spatial and single-cell analysis reveals remodeled immune microenvironment induced by synthetic oncolytic adenovirus treatment

G Liu, Q Hu, S Peng, H Ning, J Mai, X Chen, M Tao… - Cancer Letters, 2024 - Elsevier
Oncolytic viruses are multifaceted tumor killers, which can function as tumor vaccines to
boost systemic antitumor immunity. In previous study, we rationally designed a synthetic …

Influencing Factors of Survival in Hypopharyngeal Squamous Cell Cancer

GD Répássy, D Hargas, A Molnár, S Maihoub… - Journal of Clinical …, 2024 - mdpi.com
Objectives: This study examined the effects of various factors on survival in hypopharyngeal
cancer, involving a total of 100 patients. Methods: Comorbidities, treatment modalities …

超声造影定量评价顺铂联合姜黄素对喉咽癌移植瘤抗血管生成作用的价值研究

张竣豪, 梁丽, 刘佳丽, 李玲玲, 胡巧 - 广西医科大学学报, 2024 - journal.gxmu.edu.cn
目的: 探讨超声造影(CEUS) 定量分析评价顺铂联合姜黄素治疗裸鼠喉咽癌移植瘤的化疗效果及
对血管生成作用的应用价值. 方法: 建立人喉咽癌FaDu 细胞株裸鼠皮下移植瘤模型 …