Regulation of translation via mRNA structure in prokaryotes and eukaryotes

M Kozak - Gene, 2005 - Elsevier
The mechanism of initiation of translation differs between prokaryotes and eukaryotes, and
the strategies used for regulation differ accordingly. Translation in prokaryotes is usually …

Initiation of protein synthesis in bacteria

BS Laursen, HP Sørensen, KK Mortensen… - Microbiology and …, 2005 - Am Soc Microbiol
Valuable information on translation initiation is available from biochemical data and recently
solved structures. We present a detailed description of current knowledge about the …

The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403

A Bolotin, P Wincker, S Mauger, O Jaillon… - Genome …, 2001 - genome.cshlp.org
Lactococcus lactis is a nonpathogenic AT-rich gram-positive bacterium closely related to the
genus Streptococcus and is the most commonly used cheese starter. It is also the best …

Leaderless transcripts and small proteins are common features of the mycobacterial translational landscape

SS Shell, J Wang, P Lapierre, M Mir, MR Chase… - PLoS …, 2015 - journals.plos.org
RNA-seq technologies have provided significant insight into the transcription networks of
mycobacteria. However, such studies provide no definitive information on the translational …

The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection

TV Pestova, VG Kolupaeva - Genes & development, 2002 - genesdev.cshlp.org
To elucidate an outline of the mechanism of eukaryotic translation initiation, 48S complex
formation was analyzed on defined mRNAs in reactions reconstituted in vitro from fully …

[HTML][HTML] Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3

M Pioletti, F Schlünzen, J Harms, R Zarivach… - The EMBO …, 2001 - embopress.org
The small ribosomal subunit is responsible for the decoding of genetic information and plays
a key role in the initiation of protein synthesis. We analyzed by X‐ray crystallography the …

Initiation of mRNA translation in bacteria: structural and dynamic aspects

CO Gualerzi, CL Pon - Cellular and Molecular Life Sciences, 2015 - Springer
Initiation of mRNA translation is a major checkpoint for regulating level and fidelity of protein
synthesis. Being rate limiting in protein synthesis, translation initiation also represents the …

Leaderless mRNAs in bacteria: surprises in ribosomal recruitment and translational control

I Moll, S Grill, CO Gualerzi, U Bläsi - Molecular microbiology, 2002 - Wiley Online Library
It is commonly believed that the translational efficiency of prokaryotic mRNAs is intrinsically
determined by both primary and secondary structures of their translational initiation regions …

Translation initiation with 70S ribosomes: an alternative pathway for leaderless mRNAs

I Moll, G Hirokawa, MC Kiel, A Kaji… - Nucleic acids …, 2004 - academic.oup.com
It is generally accepted that translation in bacteria is initiated by 30S ribosomal subunits. In
contrast, several lines of rather indirect in vitro evidence suggest that 70S monosomes are …

The role of interactions between phage and bacterial proteins within the infected cell: a diverse and puzzling interactome

B Roucourt, R Lavigne - Environmental microbiology, 2009 - Wiley Online Library
Interactions between bacteriophage proteins and bacterial proteins are important for efficient
infection of the host cell. The phage proteins involved in these bacteriophage–host …