Role of type I interferon (IFN) in the respiratory syncytial virus (RSV) immune response and disease severity

DR Hijano, LD Vu, LM Kauvar, RA Tripp… - Frontiers in …, 2019 - frontiersin.org
Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract
disease in children< 2 years of age. Increased morbidity and mortality have been reported in …

Respiratory viral infections in patients with cancer or undergoing hematopoietic cell transplant

DR Hijano, G Maron, RT Hayden - Frontiers in microbiology, 2018 - frontiersin.org
Survival rates for pediatric cancer have steadily improved over time but it remains a
significant cause of morbidity and mortality among children. Infections are a major …

Validity of clinical severity scores for respiratory syncytial virus: a systematic review

Z Sheikh, E Potter, Y Li, RA Cohen… - The Journal of …, 2024 - academic.oup.com
Background Respiratory syncytial virus (RSV) is a widespread respiratory pathogen, and
RSV-related acute lower respiratory tract infections are the most common cause of …

Mucosal immune responses to respiratory syncytial virus

MVC Barnes, PJM Openshaw, RS Thwaites - Cells, 2022 - mdpi.com
Despite over half a century of research, respiratory syncytial virus (RSV)-induced
bronchiolitis remains a major cause of hospitalisation in infancy, while vaccines and specific …

Cytokines in the respiratory airway as biomarkers of severity and prognosis for respiratory syncytial virus infection: an update

Y Vázquez, L González, L Noguera… - Frontiers in …, 2019 - frontiersin.org
The human respiratory syncytial virus (hRSV) is one of the most important causes of upper
and lower respiratory tract infections in children and the main cause of bronchiolitis …

Systematic literature review of the signs and symptoms of respiratory syncytial virus

A Colosia, J Costello, K McQuarrie… - Influenza and other …, 2023 - Wiley Online Library
Respiratory syncytial virus (RSV) is responsible for over 30 million lower respiratory tract
infections (LRTIs) and 3 million hospitalizations worldwide each year. Despite the risk RSV …

Microbiome-transcriptome interactions related to severity of respiratory syncytial virus infection

AR Sonawane, L Tian, CY Chu, X Qiu, L Wang… - Scientific reports, 2019 - nature.com
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections and
hospital visits during infancy and childhood. Although risk factors for RSV infection have …

Identifying the research, advocacy, policy and implementation needs for the prevention and management of respiratory syncytial virus lower respiratory tract infection …

X Carbonell-Estrany, EAF Simões, LJ Bont… - Frontiers in …, 2022 - frontiersin.org
Introduction The high burden of respiratory syncytial virus (RSV) infection in young children
disproportionately occurs in low-and middle-income countries (LMICs). The PROUD …

Respiratory Syncytial Virus Disease Severity Is Associated with Distinct CD8+ T-Cell Profiles

DT Siefker, L Vu, D You, A McBride… - American journal of …, 2020 - atsjournals.org
Rationale: Respiratory syncytial virus (RSV) causes significant morbidity and mortality in
infants worldwide. Although T-helper type 2 (Th2) cell pathology is implicated in severe …

[HTML][HTML] Burden of illness in infants and young children hospitalized for respiratory syncytial virus: A rapid review

A Wingert, J Pillay, DL Moore, S Guitard… - Canada …, 2021 - ncbi.nlm.nih.gov
Respiratory syncytial virus (RSV) infections are common among young children and
represent a significant burden to patients, their families and the Canadian health system …