Formation and integration of new neurons in the adult hippocampus

A Denoth-Lippuner, S Jessberger - Nature Reviews Neuroscience, 2021 - nature.com
Neural stem cells (NSCs) generate new neurons throughout life in the mammalian brain.
Adult-born neurons shape brain function, and endogenous NSCs could potentially be …

Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories

T Hainmueller, M Bartos - Nature Reviews Neuroscience, 2020 - nature.com
The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

Adult hippocampal neurogenesis and cognitive flexibility—linking memory and mood

C Anacker, R Hen - Nature Reviews Neuroscience, 2017 - nature.com
Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

Adult neurogenesis in the hippocampus: from stem cells to behavior

JT Gonçalves, ST Schafer, FH Gage - Cell, 2016 - cell.com
The dentate gyrus of the mammalian hippocampus continuously generates new neurons
during adulthood. These adult-born neurons become functionally active and are thought to …

Mnemonic similarity task: A tool for assessing hippocampal integrity

SM Stark, CB Kirwan, CEL Stark - Trends in cognitive sciences, 2019 - cell.com
The hippocampus is critical for learning and memory, relying in part on pattern separation
processes supported by the dentate gyrus (DG) to prevent interference from overlapping …

Neurogenesis in aging and age-related neurodegenerative diseases

L Culig, X Chu, VA Bohr - Ageing research reviews, 2022 - Elsevier
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

[HTML][HTML] The molecular and systems biology of memory

ER Kandel, Y Dudai, MR Mayford - Cell, 2014 - cell.com
Learning and memory are two of the most magical capabilities of our mind. Learning is the
biological process of acquiring new knowledge about the world, and memory is the process …

Norepinephrine ignites local hotspots of neuronal excitation: How arousal amplifies selectivity in perception and memory

M Mather, D Clewett, M Sakaki… - Behavioral and Brain …, 2016 - cambridge.org
Emotional arousal enhances perception and memory of high-priority information but impairs
processing of other information. Here, we propose that, under arousal, local glutamate levels …

Bridging animal and human models of exercise-induced brain plasticity

MW Voss, C Vivar, AF Kramer, H van Praag - Trends in cognitive sciences, 2013 - cell.com
Significant progress has been made in understanding the neurobiological mechanisms
through which exercise protects and restores the brain. In this feature review, we integrate …

The hippocampus in aging and disease: from plasticity to vulnerability

T Bartsch, P Wulff - Neuroscience, 2015 - Elsevier
The hippocampus has a pivotal role in learning and in the formation and consolidation of
memory and is critically involved in the regulation of emotion, fear, anxiety, and stress …