Abstract β-thalassemia is the most common single gene disorder worldwide, in which
hemoglobin β-chain production is decreased. Today, the life expectancy of thalassemic …

Background Bone disease comprising of low bone mineral density (BMD), bone pain, and
fractures is a characteristic feature of thalassemia. Vitamin D receptors (VDRs–FokI, TaqI …

Background The study was focused on evaluating the possible correlation between
biochemical, anthropometric, and genetic indicators of osteoporosis in postmenopausal …

Introduction Sickle cell disease (SCD) patients are susceptible to the development of vitamin
D deficiency (VDD). Vitamin D through binding to vitamin D receptor (VDR) exerts its …

Bony complications are variable and common in sickle cell disease. Bone turnover markers
are a reflection of bone new bone formation or degradation. The aim of this study is to …

Osteoporosis remains an important cause of morbidity in β-thalassemia major. Although
several factors have been implicated to play an important role in the pathogenesis of …

Thalassemia major is a genetic disorder and blood transfusion is critical for survival in these
patients. Over the course of the past three decades, hyper transfusion therapy in these …

A low level of 25 hydroxy vitamin D (25 OHD) is seen more in children with sickle cell
anemia (SCA) than healthy children. SCA is common in Sudan, but the status of vitamin D is …