Helicobacter pylori Virulence Factors—Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment

J Baj, A Forma, M Sitarz, P Portincasa, G Garruti… - Cells, 2020 - mdpi.com
Gastric cancer constitutes one of the most prevalent malignancies in both sexes; it is
currently the fourth major cause of cancer-related deaths worldwide. The pathogenesis of …

Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases

A Bhattacharyya, R Chattopadhyay… - Physiological …, 2014 - journals.physiology.org
Reactive oxygen species (ROS) are generated as by-products of normal cellular metabolic
activities. Superoxide dismutase, glutathione peroxidase, and catalase are the enzymes …

Redox signaling in the gastrointestinal tract

S Pérez, R Taléns-Visconti, S Rius-Pérez… - Free Radical Biology …, 2017 - Elsevier
Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …

Helicobacter pylori and gastrointestinal tract adenocarcinomas

RM Peek Jr, MJ Blaser - Nature Reviews Cancer, 2002 - nature.com
Although gastric adenocarcinoma is associated with the presence of Helicobacter pylori in
the stomach, only a small fraction of colonized individuals develop this common malignancy …

[HTML][HTML] Helicobacter pylori persistence: biology and disease

MJ Blaser, JC Atherton - The Journal of clinical investigation, 2004 - Am Soc Clin Investig
Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from
person to person and to persistently colonize the stomach. Their population structure is a …

THE PATHOGENESIS OF HELICOBACTER PYLORI–INDUCED GASTRO-DUODENAL DISEASES

JC Atherton - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Helicobacter pylori is the main cause of peptic ulceration, distal gastric adenocarcinoma,
and gastric lymphoma. Only 15% of those colonized develop disease, and pathogenesis …

Infection-associated lymphomas derived from marginal zone B cells: a model of antigen-driven lymphoproliferation

F Suarez, O Lortholary, O Hermine, M Lecuit - Blood, 2006 - ashpublications.org
Non-Hodgkin lymphomas develop from nodal and extranodal lymphoid tissues. A distinct
subset of extranodal lymphomas arising from B cells of the marginal zone (MZ) of mucosa …

Glyphosate-based herbicides and cancer risk: a post-IARC decision review of potential mechanisms, policy and avenues of research

MJ Davoren, RH Schiestl - Carcinogenesis, 2018 - academic.oup.com
Since its initial sales in the 1970s, the herbicide glyphosate attained widespread use in
modern agriculture, becoming the most commercially successful and widely used herbicide …

Mechanisms of disease: inflammation and the origins of cancer

SF Moss, MJ Blaser - Nature clinical practice Oncology, 2005 - nature.com
Many common cancers develop as a consequence of years of chronic inflammation.
Increasing evidence indicates that the inflammation may result from persistent mucosal or …

Helicobacter pylori-Induced Inflammation: Possible Factors Modulating the Risk of Gastric Cancer

S Kumar, GK Patel, UC Ghoshal - Pathogens, 2021 - mdpi.com
Chronic inflammation and long-term tissue injury are related to many malignancies,
including gastric cancer (GC). Helicobacter pylori (H. pylori), classified as a class I …