Recent advances in potential health benefits of quercetin

F Aghababaei, M Hadidi - Pharmaceuticals, 2023 - mdpi.com
Quercetin, a flavonoid found in fruits and vegetables, has been a part of human diets for
centuries. Its numerous health benefits, including antioxidant, antimicrobial, anti …

Gut microbiota in overweight and obesity: crosstalk with adipose tissue

PD Cani, M Van Hul - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Overweight and obesity are characterized by excessive fat mass accumulation produced
when energy intake exceeds energy expenditure. One plausible way to control energy …

Theabrownin from Fu brick tea exhibits the thermogenic function of adipocytes in high-fat-diet-induced obesity

Y Wang, A Zhao, H Du, Y Liu, B Qi… - Journal of agricultural …, 2021 - ACS Publications
This study explored whether the antiobesity effect of theabrownin (TB) extracted from Fu
brick tea (FBT) was associated with the activation of brown adipose tissue (BAT) or browning …

[HTML][HTML] Non-shivering thermogenesis signalling regulation and potential therapeutic applications of brown adipose tissue

Z Zhang, D Yang, J Xiang, J Zhou, H Cao… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
In mammals, thermogenic organs exist in the body that increase heat production and
enhance energy regulation. Because brown adipose tissue (BAT) consumes energy and …

[HTML][HTML] Quercetin activates the Sestrin2/AMPK/SIRT1 axis to improve amyotrophic lateral sclerosis

T Jin, Y Zhang, BOA Botchway, M Huang, Q Lu… - Biomedicine & …, 2023 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative disease with poor
prognosis. The intricacies surrounding its pathophysiology could partly account for the lack …

Quercetin as a protective agent for liver diseases: A comprehensive descriptive review of the molecular mechanism

X Zhao, J Wang, Y Deng, L Liao, M Zhou… - Phytotherapy …, 2021 - Wiley Online Library
Quercetin is the major representative of the flavonoid subgroup of flavones, with good
pharmacological activities for the treatment of liver diseases, including liver steatosis, fatty …

Targeted delivery of nutraceuticals derived from food for the treatment of obesity and its related complications

Z Dai, Y Zhang, Y Meng, S Li, Z Suonan, Y Sun, J Ji… - Food Chemistry, 2023 - Elsevier
Nutraceuticals which are abundant in foods have attracted much attention due to their
bioactive activities of anti-obesity, anti-hyperlipidemia and anti-atherosclerosis …

UCP1 activation: hottest target in the thermogenesis pathway to treat obesity using molecules of synthetic and natural origin

U Jagtap, A Paul - Drug Discovery Today, 2023 - Elsevier
Abstract Uncoupling protein 1 (UCP1) has been discovered as a possible target for obesity
treatment because of its widespread distribution in the inner mitochondrial membrane of …

Browning of adipocytes: A potential therapeutic approach to obesity

V Schirinzi, C Poli, C Berteotti, A Leone - Nutrients, 2023 - mdpi.com
The increasing prevalence of overweight and obesity suggests that current strategies based
on diet, exercise, and pharmacological knowledge are not sufficient to tackle this epidemic …

[HTML][HTML] A Systematic Review: Quercetin—Secondary Metabolite of the Flavonol Class, with Multiple Health Benefits and Low Bioavailability

OD Frenț, L Stefan, CM Morgovan… - International …, 2024 - pmc.ncbi.nlm.nih.gov
The main goal of this systematic review on the flavonol class secondary metabolite quercetin
is to evaluate and summarize the existing research on quercetin's potential health benefits …