Background Polypharmacy and use of inappropriate medications have been linked to
increased risk of falls, hospitalizations, cognitive impairment, and death. The primary …

Aims Deprescribing is a suggested intervention to reverse the potential iatrogenic harms of
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …

Abstract Objective To develop Clinical Practice Guidelines for the screening, assessment
and management of the geriatric condition of frailty. Methods An adapted Grading of …

Objective To synthesise qualitative studies that explore prescribers' perceived barriers and
enablers to minimising potentially inappropriate medications (PIMs) chronically prescribed …

The use of multiple medicines (polypharmacy) is increasingly common in middle-aged and
older populations. Ensuring the correct balance between the prescribing of 'many'drugs and …

Background Polypharmacy, and the associated adverse drug events such as non-
adherence to prescriptions, is a common problem for elderly people living with multiple …

Background The co-administration of multiple drugs (polypharmacy) is the single most
common cause of adverse drug events in the older population, and residents of long-term …

Background Polypharmacy, common in elderly multimorbid adults, leads to increased
iatrogenic health risks. Yet, no consistent approach to stopping medicines exists in primary …

The positive benefit–risk ratio of most drugs is decreasing in correlation to very old age, the
extent of comorbidity, dementia, frailty and limited life expectancy (VOCODFLEX). First, we …

The use of multiple medicines, known as polypharmacy, poses a risk of harm that is greatest
in older adults with multimorbidity. Deprescribing aims to improve health outcomes through …