Targeting enhanced neutralizing antibody responses via increased germinal center activity: early-phase vaccine trials with novel clinical designs

WO Hahn, JA Hill, JG Kublin - Current Opinion in HIV and AIDS, 2023 - journals.lww.com
Targeting enhanced neutralizing antibody responses via incre... : Current Opinion in HIV and
AIDS Targeting enhanced neutralizing antibody responses via increased germinal center …

Sustained exposure to multivalent antigen-decorated nanoparticles generates broad anti-coronavirus responses

J Baillet, JH Klich, BS Ou, EL Meany, J Yan, TUJ Bruun… - bioRxiv, 2024 - biorxiv.org
The threat of future coronavirus pandemics requires developing cost-effective vaccine
technologies that provide broad and long-lasting protection against diverse circulating and …

Sustained vaccine exposure elicits more rapid, consistent, and broad humoral immune responses to multivalent influenza vaccines

OM Saouaf, BS Ou, YE Song, JJ Carter, J Yan, CK Jons… - bioRxiv, 2024 - biorxiv.org
With the ever-present threat of pandemics, it is imperative we develop vaccine technologies
eliciting broad and durable immunity to high-risk pathogens. Yet, current annual influenza …

Generation of an inflammatory niche in a hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines

EL Meany, JH Klich, CK Jons, T Mao, N Chaudhary… - bioRxiv, 2024 - biorxiv.org
Messenger RNA (mRNA) delivered in lipid nanoparticles (LNPs) rose to the forefront of
vaccine candidates during the COVID-19 pandemic due in part to scalability, adaptability …

Generation of an inflammatory niche in an injectable hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines

EL Meany, JH Klich, CK Jons, T Mao, N Chaudhary… - …, 2024 - pmc.ncbi.nlm.nih.gov
Messenger RNA (mRNA) delivered in lipid nanoparticles (LNPs) rose to the forefront of
vaccine candidates during the COVID-19 pandemic due in part to scalability, adaptability …