There are seven relaxin family peptides that are all structurally related to insulin. Relaxin has
many roles in female and male reproduction, as a neuropeptide in the central nervous …

Relaxin has vital physiological roles in pregnant rats, mice, and pigs. Relaxin promotes
growth and softening of the cervix, thus facilitating rapid delivery of live young. Relaxin also …

This article reviews results on diVerentiation, structure, and regulation of Leydig cells in the
testes of rodents and men. Two different populations—fetal and adult Leydig cells—can be …

Carcinoma in situ testis (CIS), also known as intratubular germ cell neoplasia (ITGCN), is a
pre-invasive precursor of testicular germ cell tumours, the commonest cancer type of male …

Cryptorchidism is the most frequent congenital birth defect in male children (2–4% in full-
term male births), and it has the potential to impact the health of the human male. In fact …

Phthalate esters are high production volume chemicals used to impart flexibility to polyvinyl
chloride products as well as other applications. In the male laboratory rat, the period of …

Ein umfassendes Nachschlagewerk mit praktischen, maßgeblichen Informationen zu allen
Aspekten der Rindertheriogenologie Die neu überarbeitete zweite Ausgabe von Bovine …

Abstract Insulin-like factor 3 (INSL3) is a small peptide hormone made and secreted
uniquely by mature Leydig cells in the testes of all mammals. Importantly, this expression …

Exposure to plasticizers di (n-butyl) phthalate (DBP) and diethylhexyl phthalate (DEHP)
during sexual differentiation causes male reproductive tract malformations in rats and …

Targeted inactivation of the insulin-like hormone 3 (insl3) gene in male mice results in
altered gubernacular development, disrupted testis decent, and cryptorchidism …