The oral microbiota: community composition, influencing factors, pathogenesis, and interventions

X Li, Y Liu, X Yang, C Li, Z Song - Frontiers in microbiology, 2022 - frontiersin.org
The human oral cavity provides a habitat for oral microbial communities. The complexity of
its anatomical structure, its connectivity to the outside, and its moist environment contribute …

Fusobacterium nucleatum and cancer

T Alon‐Maimon, O Mandelboim… - Periodontology …, 2022 - Wiley Online Library
Accumulating evidence demonstrates that the oral pathobiont Fusobacterium nucleatum is
involved in the progression of an increasing number of tumors types. Thus far, the …

Bacteriophage-mediated control of biofilm: a promising new dawn for the future

C Chang, X Yu, W Guo, C Guo, X Guo, Q Li… - Frontiers in …, 2022 - frontiersin.org
Biofilms are complex microbial microcolonies consisting of planktonic and dormant bacteria
bound to a surface. The bacterial cells within the biofilm are embedded within the …

Periodontitis: etiology, conventional treatments, and emerging bacteriophage and predatory bacteria therapies

A Łasica, P Golec, A Laskus, M Zalewska… - Frontiers in …, 2024 - frontiersin.org
Inflammatory periodontal diseases associated with the accumulation of dental biofilm, such
as gingivitis and periodontitis, are very common and pose clinical problems for clinicians …

More Than Just a Periodontal Pathogen –the Research Progress on Fusobacterium nucleatum

Y Chen, Z Huang, Z Tang, Y Huang… - Frontiers in Cellular …, 2022 - frontiersin.org
Fusobacterium nucleatum is a common oral opportunistic bacterium that can cause different
infections. In recent years, studies have shown that F. nucleatum is enriched in lesions in …

Emerging strategies for combating Fusobacterium nucleatum in colorectal cancer treatment: Systematic review, improvements and future challenges

H Liu, Y Yu, A Dong, M Elsabahy, YW Yang… - Exploration, 2024 - Wiley Online Library
Colorectal cancer (CRC) is generally characterized by a high prevalence of Fusobacterium
nucleatum (F. nucleatum), a spindle‐shaped, Gram‐negative anaerobe pathogen derived …

[HTML][HTML] The role of gut microbiota and metabolites in cancer chemotherapy

S Li, S Zhu, J Yu - Journal of Advanced Research, 2024 - Elsevier
Background The microbiota inhabits the epithelial surfaces of hosts, which influences
physiological functions from helping digest food and acquiring nutrition to regulate …

Promising dawn in tumor microenvironment therapy: engineering oral bacteria

Z Wang, W Sun, R Hua, Y Wang, Y Li… - International Journal of …, 2024 - nature.com
Despite decades of research, cancer continues to be a major global health concern. The
human mouth appears to be a multiplicity of local environments communicating with other …

Isolation and characterization of novel Fusobacterium nucleatum bacteriophages

Y Wang, Z Liu, Q Chen, L Yi, Z Xu, M Cai… - Frontiers in …, 2022 - frontiersin.org
Fusobacterium nucleatum is a strictly anaerobic, Gram-negative bacterial species that is a
member of the commensal flora in the oral cavity and gut. Recent studies suggested that the …

The human oral phageome

SP Szafrański, J Slots, M Stiesch - Periodontology 2000, 2021 - Wiley Online Library
Oral bacteriophages (or phages), especially periodontal ones, constitute a growing area of
interest, but research on oral phages is still in its infancy. Phages are bacterial viruses that …