Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Advances in biomaterial‐based spinal cord injury repair

H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …

Recent trends in decellularized extracellular matrix bioinks for 3D printing: an updated review

K Dzobo, KSCM Motaung, A Adesida - International journal of molecular …, 2019 - mdpi.com
The promise of regenerative medicine and tissue engineering is founded on the ability to
regenerate diseased or damaged tissues and organs into functional tissues and organs or …

Regenerative therapies for spinal cord injury

N Ashammakhi, HJ Kim, A Ehsanipour… - … Engineering Part B …, 2019 - liebertpub.com
Spinal cord injury (SCI) is a serious problem that primarily affects younger and middle-aged
adults at its onset. To date, no effective regenerative treatment has been developed. Over …

Minimally invasive and regenerative therapeutics

N Ashammakhi, S Ahadian, MA Darabi… - Advanced …, 2019 - Wiley Online Library
Advances in biomaterial synthesis and fabrication, stem cell biology, bioimaging,
microsurgery procedures, and microscale technologies have made minimally invasive …

Polymer scaffolds facilitate spinal cord injury repair

Q Zhang, B Shi, J Ding, L Yan, JP Thawani, C Fu… - Acta biomaterialia, 2019 - Elsevier
During the past decades, improving patient neurological recovery following spinal cord
injury (SCI) has remained a challenge. An effective treatment for SCI would not only reduce …

Emerging bone tissue engineering via Polyhydroxyalkanoate (PHA)-based scaffolds

J Lim, M You, J Li, Z Li - Materials Science and Engineering: C, 2017 - Elsevier
Polyhydroxyalkanoates (PHAs) are a class of biodegradable polymers derived from
microorganisms. On top of their biodegradability and biocompatibility, different PHA types …

Current concepts of biomaterial scaffolds and regenerative therapy for spinal cord injury

H Suzuki, Y Imajo, M Funaba, H Ikeda… - International Journal of …, 2023 - mdpi.com
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …

Porous polyelectrolytes: the interplay of charge and pores for new functionalities

W Zhang, Q Zhao, J Yuan - Angewandte Chemie International …, 2018 - Wiley Online Library
The past decade has witnessed rapid advances in porous polyelectrolytes and there is
tremendous interest in their synthesis as well as their applications in environmental, energy …

Chasing the paradigm: clinical translation of 25 years of tissue engineering

T Hoffman, A Khademhosseini… - Tissue Engineering Part …, 2019 - liebertpub.com
In the past 25 years, the tissue engineering field has made incredible strides in developing
tangible therapies for patients in need. Applications of the tissue engineering paradigm …