Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics

K Zhang, Q Feng, Z Fang, L Gu, L Bian - Chemical Reviews, 2021 - ACS Publications
Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …

3D spatiotemporal mechanical microenvironment: a hydrogel‐based platform for guiding stem cell fate

Y Ma, M Lin, G Huang, Y Li, S Wang, G Bai… - Advanced …, 2018 - Wiley Online Library
Stem cells hold great promise for widespread biomedical applications, for which stem cell
fate needs to be well tailored. Besides biochemical cues, accumulating evidence has …

Reconstructable gradient structures and reprogrammable 3D deformations of hydrogels with coumarin units as the photolabile crosslinks

CN Zhu, CY Li, H Wang, W Hong, F Huang… - Advanced …, 2021 - Wiley Online Library
Morphing hydrogels have versatile applications in soft robotics, flexible electronics, and
biomedical devices. Controlling component distribution and internal stress within a hydrogel …

Spatially and temporally controlled hydrogels for tissue engineering

J Leijten, J Seo, K Yue, G Trujillo-de Santiago… - Materials Science and …, 2017 - Elsevier
Recent years have seen tremendous advances in the field of hydrogel-based biomaterials.
One of the most prominent revolutions in this field has been the integration of elements or …

Recent advances in bio-orthogonal and dynamic crosslinking of biomimetic hydrogels

MR Arkenberg, HD Nguyen, CC Lin - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
In recent years, dynamic,'click'hydrogels have been applied in numerous biomedical
applications. Owing to the mild, cytocompatible, and highly specific reaction kinetics, a …

Viscoelasticity in natural tissues and engineered scaffolds for tissue reconstruction

D Huang, Y Huang, Y Xiao, X Yang, H Lin, G Feng… - Acta biomaterialia, 2019 - Elsevier
Viscoelasticity of living tissues plays a critical role in tissue homeostasis and regeneration,
and its implication in disease development and progression is being recognized recently. In …

Photoreversible covalent hydrogels for soft-matter additive manufacturing

CP Kabb, CS O'Bryan, CC Deng… - … applied materials & …, 2018 - ACS Publications
Reversible covalent chemistry provides access to robust materials with the ability to be
degraded and reformed upon exposure to an appropriate stimulus. Photoresponsive units …

Chemical cross-linking methods for cell encapsulation in hydrogels

C Echalier, L Valot, J Martinez, A Mehdi… - Materials Today …, 2019 - Elsevier
Cell-encapsulating hydrogels are of tremendous interest in regenerative medicine. Tissue
engineering relies on biomaterials able to act as artificial extracellular matrices to guide cells …

Temperature and pH responsive hydrogels using methacrylated lignosulfonate cross-linker: synthesis, characterization, and properties

C Jin, W Song, T Liu, J Xin, WC Hiscox… - ACS Sustainable …, 2018 - ACS Publications
In this work, biobased hydrogels with temperature and pH responsive properties were
prepared by copolymerizing N-isopropylacrylamide (NIPAM), itaconic acid (IA), and …

Dynamic hydrogels with viscoelasticity and tunable stiffness for the regulation of cell behavior and fate

Y Zhang, Z Wang, Q Sun, Q Li, S Li, X Li - Materials, 2023 - mdpi.com
The extracellular matrix (ECM) of natural cells typically exhibits dynamic mechanical
properties (viscoelasticity and dynamic stiffness). The viscoelasticity and dynamic stiffness of …