Immune privilege in corneal transplantation

J Hori, T Yamaguchi, H Keino, P Hamrah… - Progress in retinal and …, 2019 - Elsevier
Corneal transplantation is the most successful solid organ transplantation performed in
humans. The extraordinary success of orthotopic corneal allografts, in both humans and …

Corneal graft rejection

A Panda, M Vanathi, A Kumar, Y Dash, S Priya - Survey of ophthalmology, 2007 - Elsevier
Penetrating keratoplasty is the most widely practiced type of transplantation in humans.
Irreversible immune rejection of the transplanted cornea is the major cause of human …

[HTML][HTML] Gene therapy in the anterior eye segment

C Amador, R Shah, S Ghiam, AA Kramerov… - Current gene …, 2022 - ncbi.nlm.nih.gov
This review provides comprehensive information about the advances in gene therapy in the
anterior segment of the eye, including cornea, conjunctiva, lacrimal gland, and trabecular …

From waste to wealth: Repurposing slaughterhouse waste for xenotransplantation

RL Khan, AA Khraibi, LF Dumée… - … in Bioengineering and …, 2023 - frontiersin.org
Slaughterhouses produce large quantities of biological waste, and most of these materials
are underutilized. In many published reports, the possibility of repurposing this form of waste …

The impact of corneal allograft rejection on the long-term outcome of corneal transplantation

DJ Coster, KA Williams - American journal of ophthalmology, 2005 - Elsevier
PURPOSE: To examine the influence of corneal allograft rejection on the survival of
penetrating corneal transplantation, to review the status of conventional therapies to improve …

Ultrathin chitosan–poly (ethylene glycol) hydrogel films for corneal tissue engineering

B Ozcelik, KD Brown, A Blencowe, M Daniell… - Acta biomaterialia, 2013 - Elsevier
Due to the high demand for donor corneas and their low supply, autologous corneal
endothelial cell (CEC) culture and transplantation for treatment of corneal endothelial …

Visual outcome in corneal grafts: a preliminary analysis of the Swedish Corneal Transplant Register

M Claesson, WJ Armitage, P Fagerholm… - British Journal of …, 2002 - bjo.bmj.com
Aim: To assess visual outcome and the incidence of complications at 2 years postoperatively
in corneal grafts reported to the Swedish Corneal Transplant Register. Methods …

In Vitro Systems for Tissue Engineering

WT Godbey, A Atala - Annals of the new York Academy of …, 2002 - Wiley Online Library
Tissue engineering, by necessity, encompasses a wide array of experimental directions and
scientific disciplines. In vitro tissue engineering involves the manipulation of cells in vitro …

Function of indoleamine 2, 3‐dioxygenase in corneal allograft rejection and prolongation of allograft survival by over‐expression

SC Beutelspacher, R Pillai, MP Watson… - European journal of …, 2006 - Wiley Online Library
Abstract Indoleamine 2, 3‐dioxygenase (IDO) suppresses T cell responses by its action in
catabolising tryptophan. It is important in maintenance of immune privilege in the placenta …

Lentiviral vectors for ocular gene therapy

Y Arsenijevic, A Berger, F Udry, C Kostic - Pharmaceutics, 2022 - mdpi.com
This review offers the basics of lentiviral vector technologies, their advantages and pitfalls,
and an overview of their use in the field of ophthalmology. First, the description of the global …