Candidate genes and pathways in cervical cancer: A systematic review and integrated bioinformatic analysis

MH Elias, S Das, N Abdul Hamid - Cancers, 2023 - mdpi.com
Simple Summary Cervical cancer is the fourth most common cancer among women
worldwide. Although many recommendations on the screening, diagnosis, and treatment of …

Machine Learning analysis of high-grade serous ovarian cancer proteomic dataset reveals novel candidate biomarkers

F Farinella, M Merone, L Bacco, A Capirchio… - Scientific Reports, 2022 - nature.com
Ovarian cancer is one of the most common gynecological malignancies, ranking third after
cervical and uterine cancer. High-grade serous ovarian cancer (HGSOC) is one of the most …

Exploring the utility of FTS as a bonafide binding partner for EGFR: A potential drug target for cervical cancer

S Krishnamoorthy, B Muruganantham, JR Yu… - Computers in Biology …, 2023 - Elsevier
Establishment of human papilloma virus (HPV) infection and its progression to cervical
cancer (CC) requires the participation of epidermal growth factor (EGF) receptor (EGFR) and …

Bioinformatics analysis of differentially expressed genes and pathways in the development of cervical cancer

B Wu, S Xi - BMC cancer, 2021 - Springer
Background This study aimed to explore and identify key genes and signaling pathways that
contribute to the progression of cervical cancer to improve prognosis. Methods Three gene …

Bioinformatics analysis of the transcriptional expression of minichromosome maintenance proteins as potential indicators of survival in patients with cervical cancer

B Wu, S Xi - BMC cancer, 2021 - Springer
Background As major regulators of DNA replication in eukaryotes, minichromosome
maintenance (MCM) proteins play an important role in the initiation and extension of DNA …

[HTML][HTML] Multiple microarray analyses identify key genes associated with the development of non-small cell lung cancer from chronic obstructive pulmonary disease

L Zhang, J Chen, H Yang, C Pan, H Li, Y Luo… - Journal of …, 2021 - ncbi.nlm.nih.gov
Introduction: Chronic obstructive pulmonary disease (COPD) is an independent risk factor of
non-small cell lung cancer (NSCLC). This study aimed to analyze the key genes and …

[HTML][HTML] Identification of novel MCM2 inhibitors from Catharanthus roseus by pharmacoinformatics, molecular docking and molecular dynamics simulation-based …

KMS Andalib, P Biswas, MR Sakib, MN Hasan… - Informatics in Medicine …, 2023 - Elsevier
Nearly all living cells undergo DNA replication in order to duplicate their genome; this multi-
step biological process is tightly regulated by different cellular machineries and numerous …

Identification of hub genes as potential prognostic biomarkers in cervical cancer using comprehensive bioinformatics analysis and validation studies

H Xue, Z Sun, W Wu, D Du, S Liao - Cancer Management and …, 2021 - Taylor & Francis
Background Cervical cancer belongs to one of the most common female cancers; yet, the
exact underlying mechanisms are still elusive. Recently, microarray and sequencing …

High MCM6 expression as a potential prognostic marker in clear-cell renal cell carcinoma

NR Jang, J Baek, Y Ko, PH Song, MJ Gu - in vivo, 2021 - iv.iiarjournals.org
Aim: Minichromosome maintenance (MCM) proteins are involved in initiation of DNA
replication and cell-cycle progression. Loss of MCM function results in genomic instability …

TOP2A/MCM2, p16INK4a, and cyclin E1 expression in liquid-based cytology: a biomarkers panel for progression risk of cervical premalignant lesions

O Del Moral-Hernández, D Hernández-Sotelo… - BMC cancer, 2021 - Springer
Background To improve the efficiency of early diagnosis systems for cervical cancer, the use
of cellular and viral markers for identifying precancerous lesions with a greater probability to …