Major histocompatibility complex (MHC) class I and MHC class II proteins: conformational plasticity in antigen presentation

M Wieczorek, ET Abualrous, J Sticht… - Frontiers in …, 2017 - frontiersin.org
Antigen presentation by major histocompatibility complex (MHC) proteins is essential for
adaptive immunity. Prior to presentation, peptides need to be generated from proteins that …

Activating and inhibitory receptors of natural killer cells

HJ Pegram, DM Andrews, MJ Smyth… - Immunology and cell …, 2011 - Wiley Online Library
Natural killer (NK) cells are potent immune effector cells that can respond to infection and
cancer, as well as allowing maternal adaptation to pregnancy. In response to malignant …

Grading the commercial optical biosensor literature—Class of 2008:'The Mighty Binders'

RL Rich, DG Myszka - Journal of Molecular Recognition: An …, 2010 - Wiley Online Library
Optical biosensor technology continues to be the method of choice for label‐free, real‐time
interaction analysis. But when it comes to improving the quality of the biosensor literature …

Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition

Y Li, M Hofmann, Q Wang, L Teng, LK Chlewicki… - Immunity, 2009 - cell.com
The cytolytic activity of natural killer (NK) cells is regulated by inhibitory receptors that detect
the absence of self molecules on target cells. Structural studies of missing self recognition …

Co‐evolution of MHC class I and variable NK cell receptors in placental mammals

LA Guethlein, PJ Norman, HG Hilton… - Immunological …, 2015 - Wiley Online Library
Shaping natural killer (NK) cell functions in human immunity and reproduction are diverse
killer cell immunoglobulin‐like receptors (KIR s) that recognize polymorphic MHC class I …

[图书][B] Animal lectins: form, function and clinical applications

GS Gupta - 2012 - books.google.com
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …

Structural basis for recognition of cellular and viral ligands by NK cell receptors

Y Li, RA Mariuzza - Frontiers in immunology, 2014 - frontiersin.org
Natural killer (NK) cells are key components of innate immune responses to tumors and viral
infections. NK cell function is regulated by NK cell receptors that recognize both cellular and …

Dynamics of MHC-I molecules in the antigen processing and presentation pathway

HV Truong, NG Sgourakis - Current opinion in immunology, 2021 - Elsevier
Highlights•MHC-I molecules exhibit allotype-dependent conformational flexibility, which is
critical for their function.•Peptide-deficient MHC-I adopt distinct groove conformations …

Distinct MHC class I–dependent NK cell–activating receptors control cytomegalovirus infection in different mouse strains

M Pyzik, B Charbonneau… - Journal of Experimental …, 2011 - rupress.org
Recognition of mouse cytomegalovirus (MCMV)–infected cells by activating NK cell
receptors was first described in the context of Ly49H, which confers resistance to C57BL/6 …

CD4 and CD8: an inside-out coreceptor model for innate immune cells

D Gibbings, AD Befus - Journal of leukocyte biology, 2009 - academic.oup.com
CD4 and CD8 enhancement of FcR-like signaling is discussed as a potential role when
expressed by innate immune cells. CD8 and CD4 are expressed by several cell types that …