High-throughput transcriptome analyses from ASPIRO, a phase 1/2/3 study of gene replacement therapy for X-linked myotubular myopathy
X-linked myotubular myopathy (XLMTM) is a severe congenital disease characterized by
profound muscle weakness, respiratory failure, and early death. No approved therapy for …
profound muscle weakness, respiratory failure, and early death. No approved therapy for …
A clinical protocol for a German birth cohort study of the Maturation of Immunity Against respiratory viral Infections (MIAI)
CR Hartmann, R Khan, J Schöning, M Richter… - Frontiers in …, 2024 - frontiersin.org
Introduction Respiratory viral infections (RVIs) are a major global contributor to morbidity
and mortality. The susceptibility and outcome of RVIs are strongly age-dependent and show …
and mortality. The susceptibility and outcome of RVIs are strongly age-dependent and show …
Data Integration from Heterogeneous Control Levels for the Purposes of Analysis within Industry 4.0 Concept
T Horak, P Strelec, M Kebisek, P Tanuska, A Vaclavova - Sensors, 2022 - mdpi.com
Small-and medium-sized manufacturing companies must adapt their production processes
more quickly. The speed with which enterprises can apply a change in the context of data …
more quickly. The speed with which enterprises can apply a change in the context of data …
MIAI: Maturation of Immunity Against Influenza-a German birth cohort study with focus on the development of immunity against respiratory viral infections
CR Hartmann, R Khan, J Schoening, M Richter… - medRxiv, 2024 - medrxiv.org
Respiratory viral infections (RVIs) are a major global contributor to morbidity and mortality.
The susceptibility and outcome of RVIs are strongly age-dependent and show considerable …
The susceptibility and outcome of RVIs are strongly age-dependent and show considerable …
Developmental programming of kupffer cells by maternal obesity causes fatty liver disease in the offspring
Kupffer cells (KCs) are tissue-resident macrophages which colonize the developing liver
early during embryogenesis 1. Throughout development and adulthood, KCs have distinct …
early during embryogenesis 1. Throughout development and adulthood, KCs have distinct …
[HTML][HTML] hCoCena: A toolbox for network-based co-expression analysis and horizontal integration of transcriptomic datasets
As the number and complexity of transcriptomic datasets increase, there is a rising demand
for accessible and user-friendly analysis tools. Here, we present hCoCena (horizontal …
for accessible and user-friendly analysis tools. Here, we present hCoCena (horizontal …
TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism
AF Feiten, K Dahm, B van Lengerich, JH Suh… - bioRxiv, 2024 - biorxiv.org
Triggering receptor expressed on myeloid cells 2 (TREM2) is a central regulator of microglial
activity and sequence variants are major risk factors for late onset Alzheimer's disease …
activity and sequence variants are major risk factors for late onset Alzheimer's disease …
Improving prognostication and treatment choices for patients with AML
A Österroos - 2023 - diva-portal.org
Improving prognostication and treatment choices for patients with AML diva-portal.org
Digitala Vetenskapliga Arkivet Simple search Advanced search - Research publications …
Digitala Vetenskapliga Arkivet Simple search Advanced search - Research publications …
[HTML][HTML] Human variation in population-wide gene expression data predicts gene perturbation phenotype
Population-scale datasets of healthy individuals capture genetic and environmental factors
influencing gene expression. The expression variance of a gene of interest (GOI) can be …
influencing gene expression. The expression variance of a gene of interest (GOI) can be …