Mesenchymal gastrointestinal cancers are represented by the gastrointestinal stromal
tumors (GISTs) which occur throughout the whole gastrointestinal tract, and affect human …

Cancer treatments have recently shifted from broad-spectrum cytotoxic therapies to more
focused treatments, maximizing anticancerous activity while reducing toxicity to healthy …

Gastrointestinal stromal tumor (GIST) is the most common sarcoma located in
gastrointestinal tract and derived from the interstitial cell of Cajal (ICC) lineage. Both ICC …

Gastrointestinal stromal tumors (GIST) are the most common stromal‑derived tumors of the
gastrointestinal tract and have a potential metastatic capacity in almost half of all cases, with …

Background Previous studies have confirmed that preoperative nutritional-inflammatory
indicators can predict prognosis in various malignancies. However, to the best of our …

摘要近年来, 随着新研究证据的出现, 胃肠间质瘤(GISTs) 领域的国内外指南随之作出更新,
从GISTs 诊断, 生物学行为, 手术治疗到靶向药物治疗, 几乎涵盖了GISTs 管理的每个环节 …

Background c-Kit protein is a signal transduction protein involved in multiple signal
pathways, which play an important role in a variety of cellular events such as cell …

As one of the most common mesenchymal malignancies in the digestive system,
gastrointestinal stromal tumors (GISTs) occur throughout the alimentary tract with diversified …

Background It is urgent to explore the pathogenic mechanism of gastrointestinal stromal
tumours (GISTs). KDM6A, a histone demethylase, can activate gene transcription and has …

KRAS is the most commonly mutated oncogene in human cancers. Targeted therapy and
immunotherapy for this gene have made remarkable progress in recent years. However …