Mitochondria evolved from alpha-proteobacteria captured within a host between two and
three billion years ago. This origin resulted in the formation of a double-layered organelle …

Tumor growth and progression are complex processes mediated by mutual interactions
between cancer cells and their surrounding stroma that include diverse cell types and …

Background Dysregulation of both mitochondrial biogenesis and mitophagy is critical to
sustain oncogenic signaling pathways. However, the mechanism of mitophagy in promoting …

Recently, microRNAs have emerged as regulators of cancer metastasis through acting on
multiple signaling pathways involved in metastasis. In this study, we have analyzed the level …

In this study, we aimed to develop a multifunctional drug/gene delivery system for the
treatment of glioblastoma multiforme by combining the ligand-mediated active targeting and …

The stomatin-domain defines a family of proteins that are found in all classes of life. The
ubiquity of stomatin-family proteins and their high degree of homology suggest that they …

Current predictive tools and imaging modalities are not accurate enough for preoperative
diagnosis of lymph node metastatic prostate cancer (LNM PCa). Proteomic analysis is …

S100A14 is an EF-hand containing calcium-binding protein of the S100 protein family that
exerts its biological effects on different types of cells. However, exact extracellular roles of …

Thermosensitive cationic magnetic liposomes (TCMLs), prepared from
dipalmitoylphosphatidylcholine (DPPC), cholesterol, 1, 2-distearoyl-sn-glycero-3 …

Magnetic nanoparticles (MNPs) are useful for magnetic targeted drug delivery while ligand-
mediated active targeting is another common delivery strategy for cancer therapy. In this …