Nausea and vomiting are common gastrointestinal complaints that can be triggered by
diverse emetic stimuli through central and/or peripheral nervous systems. Both nausea and …

Human neuropeptide Y (hNPY) is one of the most widely expressed neurotransmitters in the
human central and peripheral nervous systems. It consists of 36 highly conserved amino …

Communication between glia cells and neurons is crucial for brain functions, but the
molecular mechanisms and functional consequences of gliotransmission remain enigmatic …

The human neuropeptide Y (NPY) Y2 receptor (Y2R) plays essential roles in food intake,
bone formation and mood regulation, and has been considered an important drug target for …

The nervous system mediates key airway protective behaviors, including cough, mucus
secretion, and airway smooth muscle contraction. Thus, its involvement and potential …

Consumption of deoxynivalenol (DON), a trichothecene mycotoxin known to commonly
contaminate grain-based foods, suppresses growth of experimental animals, thus raising …

Background The gut microbiota controls broad aspects of human metabolism and feeding
behavior, but the basis for this control remains largely unclear. Given the key role of human …

There is growing evidence that neuropeptide Y (NPY) acting through Y1 and Y2 receptors
has a prominent role in modulating anxiety-and depression-like behavior in rodents …

A peptide composed of a 36 amino acid called Neuropeptide Y (NPY) is employed in a
variety of physiological processes to manage and treat conditions affecting the endocrine …

Lipidation is a powerful strategy to improve the stability in vivo of peptide drugs. Attachment
of a lipid chain to a hydrophilic peptide leads to amphiphilicity and the potential for surfactant …