Significant progress has recently been made in our understanding of animal regenerative
biology, spurred on by the use of a wider range of model organisms and an increasing …

The discovery of Hydra regeneration by Abraham Trembley in 1744 promoted much
scientific curiosity thanks to his clever design of experimental strategies away from the …

Sea anemones are seemingly primitive animals that, along with corals, jellyfish, and hydras,
constitute the oldest eumetazoan phylum, the Cnidaria. Here, we report a comparative …

New perspectives on the origin of neurogenesis emerged with the identification of genes
encoding post-synaptic proteins as well as many “neurogenic” regulators as the NK, Six …

The nuclear receptors (NRs) of metazoans are an ancient family of transcription factors
defined by conserved DNA-and ligand-binding domains (DBDs and LBDs, respectively) …

DNA that controls gene expression (eg enhancers, promoters) has seemed almost never to
be conserved between distantly related animals, like vertebrates and arthropods. This is …

Nematogenesis, the production of stinging cells (nematocytes) in Cnidaria, can be
considered as a model neurogenic process. Most molecular data concern the freshwater …

The cnidarian model organism Hydra has long been studied for its remarkable ability to
regenerate its head, which is controlled by a head organizer located near the hypostome …

Since the discovery of radial glia as the source of neurons, their heterogeneity in regard to
neurogenesis has been described by clonal and time-lapse analysis in vitro. However, the …

After bisection, Hydra polyps regenerate their head from the lower half thanks to a head‐
organizer activity that is rapidly established at the tip. Head regeneration is also highly …