Helicobacter pylori Virulence Factors—Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment

J Baj, A Forma, M Sitarz, P Portincasa, G Garruti… - Cells, 2020 - mdpi.com
Gastric cancer constitutes one of the most prevalent malignancies in both sexes; it is
currently the fourth major cause of cancer-related deaths worldwide. The pathogenesis of …

The impacts of H. pylori virulence factors on the development of gastroduodenal diseases

WL Chang, YC Yeh, BS Sheu - Journal of biomedical science, 2018 - Springer
Although most H. pylori infectors are asymptomatic, some may develop serious disease,
such as gastric adenocarcinoma, gastric high-grade B cell lymphoma and peptic ulcer …

Helicobacter pylori diversity and gastric cancer risk

TL Cover - MBio, 2016 - Am Soc Microbiol
Gastric cancer is a leading cause of cancer-related death worldwide. Helicobacter pylori
infection is the strongest known risk factor for this malignancy. An important goal is to identify …

Helicobacter pylori Virulence Factor Cytotoxin-Associated Gene A (CagA)-Mediated Gastric Pathogenicity

S Ansari, Y Yamaoka - International journal of molecular sciences, 2020 - mdpi.com
Helicobacter pylori causes persistent infection in the gastric epithelium of more than half of
the world's population, leading to the development of severe complications such as peptic …

Pathogenesis of Helicobacter pylori Infection

S Backert, M Clyne - Helicobacter, 2011 - Wiley Online Library
Helicobacter pylori infections and clinical outcome are dependent on sophisticated
interactions between the bacteria and its host. Crucial bacterial factors associated with …

Helicobacter pylori in the Oral Cavity: Current Evidence and Potential Survival Strategies

L Zhang, X Chen, B Ren, X Zhou, L Cheng - International journal of …, 2022 - mdpi.com
Helicobacter pylori (H. pylori) is transmitted primarily through the oral–oral route and fecal–
oral route. The oral cavity had therefore been hypothesized as an extragastric reservoir of H …

A review on the research progress on non-pharmacological therapy of Helicobacter pylori

Q Luo, N Liu, S Pu, Z Zhuang, H Gong… - Frontiers in …, 2023 - frontiersin.org
Helicobacter pylori is a pathogenic microorganism that mainly resides in the human stomach
and is the major cause of chronic gastritis, peptic ulcer and gastric cancer. Up to now, the …

Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis

SC Stein, E Faber, SH Bats, T Murillo, Y Speidel… - PLoS …, 2017 - journals.plos.org
Highly virulent Helicobacter pylori cause proinflammatory signaling inducing the
transcriptional activation and secretion of cytokines such as IL-8 in epithelial cells …

The role of T helper 1-cell response in Helicobacter pylori-infection

N Bagheri, L Salimzadeh, H Shirzad - Microbial pathogenesis, 2018 - Elsevier
Helicobacter pylori (H. pylori) is a human pathogen affecting over 50% of the world
population. This pathogen is usually associated with chronic inflammation of the gastric …

Helicobacter pylori Strains and Gastric MALT Lymphoma

P Floch, F Mégraud, P Lehours - Toxins, 2017 - mdpi.com
This article summarizes the main findings concerning Helicobacter pylori associated with
gastric MALT lymphoma (GML). Considered together, GML strains based on their virulence …