Abstract Bisphenol A (BPA; 4, 4′-isopropylidenediphenol) is an endocrine disruptor that is
used as a material for the production of phenol resins, polyacrylates, polyesters, epoxy …

Tetraspanins are molecular scaffolds that distribute proteins into highly organized
microdomains consisting of adhesion, signaling, and adaptor proteins. Many reports have …

The AGC family of serine/threonine kinases (PKA, PKG, PKC) includes more than 60
members that are critical regulators of numerous cellular functions, including cell cycle and …

Protein kinase C (PKC) isozymes have remained elusive cancer targets despite the
unambiguous tumor promoting function of their potent ligands, phorbol esters, and the …

Risk of cancer especially of colon, breast, and pancreas is high in diabetic and obese
patients, with potential involvement of augmented expression of RAGE (receptor for …

Marine sponges have been considered as a drug treasure house with respect to great
potential regarding their secondary metabolites. Most of the studies have been conducted …

Protein kinase C (PKC) comprises a family of lipid-sensitive enzymes that have been
involved in a broad range of cellular functions. PKC-α is a member of classical PKC with …

Objective: Genistein is a recognized isoflavone present in soybeans with antioxidant, anti-
inflammatory, antiangiogenic and antitumor activities. This study aimed to test ability of …

Protein kinase C (PKC), a family of phospholipid-dependent serine/threonine kinase, is
classed into three subfamilies based on their structural and activation characteristics …

Triple-negative breast cancer (TNBC) is a subtype of breast cancer lacking targeted therapy
currently. Recent studies imply that protein kinase C may play important roles in TNBC …