Bronchiectasis

JD Chalmers, AB Chang, SH Chotirmall… - Nature reviews Disease …, 2018 - nature.com
Bronchiectasis refers to abnormal dilatation of the bronchi. Airway dilatation can lead to
failure of mucus clearance and increased risk of infection. Pathophysiological mechanisms …

European Respiratory Society guidelines for the management of children and adolescents with bronchiectasis

AB Chang, R Fortescue, K Grimwood… - European …, 2021 - Eur Respiratory Soc
There is increasing awareness of bronchiectasis in children and adolescents, a chronic
pulmonary disorder associated with poor quality of life for the child/adolescent and their …

COVID-19 cough classification using machine learning and global smartphone recordings

M Pahar, M Klopper, R Warren, T Niesler - Computers in Biology and …, 2021 - Elsevier
We present a machine learning based COVID-19 cough classifier which can discriminate
COVID-19 positive coughs from both COVID-19 negative and healthy coughs recorded on a …

COVID-19 detection in cough, breath and speech using deep transfer learning and bottleneck features

M Pahar, M Klopper, R Warren, T Niesler - Computers in biology and …, 2022 - Elsevier
We present an experimental investigation into the effectiveness of transfer learning and
bottleneck feature extraction in detecting COVID-19 from audio recordings of cough, breath …

Protracted bacterial bronchitis: the last decade and the road ahead

AB Chang, JW Upham, IB Masters… - Pediatric …, 2016 - Wiley Online Library
Cough is the single most common reason for primary care physician visits and, when
chronic, a frequent indication for specialist referrals. In children, a chronic cough (> 4 weeks) …

A multicenter study on chronic cough in children: burden and etiologies based on a standardized management pathway

AB Chang, CF Robertson, PP Van Asperen… - Chest, 2012 - Elsevier
Background While the burden of chronic cough in children has been documented, etiologic
factors across multiple settings and age have not been described. In children with chronic …

Management of children with chronic wet cough and protracted bacterial bronchitis: CHEST guideline and expert panel report

AB Chang, JJ Oppenheimer, MM Weinberger… - Chest, 2017 - Elsevier
Background Wet or productive cough is common in children with chronic cough. We
formulated recommendations based on systematic reviews related to the management of …

Automatic cough classification for tuberculosis screening in a real-world environment

M Pahar, M Klopper, B Reeve, R Warren… - Physiological …, 2021 - iopscience.iop.org
Objective. The automatic discrimination between the coughing sounds produced by patients
with tuberculosis (TB) and those produced by patients with other lung ailments. Approach …

Protracted bacterial bronchitis in children: natural history and risk factors for bronchiectasis

DF Wurzel, JM Marchant, ST Yerkovich, JW Upham… - Chest, 2016 - Elsevier
Background Protracted bacterial bronchitis (PBB) and bronchiectasis are distinct diagnostic
entities that share common clinical and laboratory features. It is postulated, but remains …

Pediatric bronchiectasis: no longer an orphan disease

V Goyal, K Grimwood, J Marchant… - Pediatric …, 2016 - Wiley Online Library
Bronchiectasis is described classically as a chronic pulmonary disorder characterized by a
persistent productive cough and irreversible dilatation of one or more bronchi. However, in …